Evidence map›Paper›PMID 37670716›Full record

Trial reportCurrent drug discovery technologies2024

The Effect of Aloe vera on the Healing of Diabetic Foot Ulcer: A Randomized, Double-blind Clinical Trial.

Parichehr Sabaghzadeh Irani, Hadi Ranjbar, Roghayeh Mehdipour-Rabori, Mahya Torkaman, Sudabeh Amirsalari, Farshid Alazmani-Noodeh

Abstract readRandomized Controlled Trial
PubMed Publisher
In one paragraph

Trial report in Current drug discovery technologies, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.2field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 6 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Review
  5. Foods (Basel, Switzerland) · 2024
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 4 institutions in 1 country.

Parichehr Sabaghzadeh IraniDepartment of Nursing and Midwifery, Student Research Committee, Kerman University of Medical Sciences, Kerman, Iran.ORCID 0000-0003-3760-5524
Hadi RanjbarMental Health Research Center, Psychosocial Health Research Institute, Iran University of Medical Sciences, Tehran, Iran.ORCID 0000-0002-3672-7266
Roghayeh Mehdipour-RaboriRazi Faculty of Nursing and Midwifery, Department of Medical-surgical Nursing, Nursing Research Nursing, Kerman University of Medical Science, Kerman, Iran.ORCID 0000-0002-7608-9545
Mahya TorkamanStudent Research Committee, Kerman University of Medical Sciences, Kerman, Iran.ORCID 0000-0002-9166-6435
Sudabeh AmirsalariDepartment of Reproductive Health Midwifery, School of Nursing & Midwifery, Tehran University of Medical Sciences, Tehran, Iran.ORCID 0000-0003-3744-6578
Farshid Alazmani-NoodehCritical Care Nursing Department, Faculty of Nursing, Aja University of Medical Sciences, Tehran, Iran.ORCID 0000-0002-1501-1648
Kerman University of Medical Sciences · IRAja University of Medical Sciences · IRIran University of Medical Sciences · IRTehran University of Medical Sciences · IR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundDiabetic foot ulcer (DFU) is a prevalent complication of diabetes that can result in severe consequences. The cost of treating DFUs is high, and there is a lack of new therapies available in developing countries. This has created a demand for complementary and alternative treatments. The objective of this study was to assess the impact of aloe vera gel on the healing process of diabetic foot ulcers. MATERIALS AND

methodsThe study was a double-blind, randomized, controlled clinical trial. The study samples were 66 patients with diabetic foot ulcers who were randomly assigned to two groups (intervention and control). All ulcers in both groups were washed with normal saline and dressed in sterile gauze. The ulcers in the intervention group were covered with a thin layer of Aloe Vera gel before the dressing. The Bates-Jensen Wound Assessment Tool (BWAT) was used on three occasions, including before the intervention period and at the end of each week. Data were analyzed using SPSS 16.

resultsAfter three weeks, there was a notable contrast in the recovery pattern of the two groups. The patients who had aloe vera gel added to their dressing showed a more substantial decrease in the mean scores of their BWAT.

conclusionThese findings are promising and suggest that Aloe vera may be a safe and effective adjunctive treatment for diabetic foot ulcers. However, further research is needed to confirm these results and to investigate the underlying mechanisms of aloe vera's therapeutic effect on diabetic foot ulcers.

Indexed as

AloeDiabetic FootWound HealingAdultAgedBandagesDouble-Blind MethodFemaleHumansMaleMiddle AgedPhytotherapyPlant PreparationsTreatment OutcomeAloe vera gelPlant PreparationsAloe veracomplementarydiabetic foot ulcerdrugtrial.wound

Identifiers

PMID37670716
OpenAlexW4386466895

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.