Evidence map›Paper›PMID 37670516›Full record

ReviewEuropean journal of ophthalmology2024

Precisional modulation of translaminar pressure gradients for ophthalmic diseases.

Ethan Waisberg, Joshua Ong, Mouayad Masalkhi, Phani Paladugu, Andrew G Lee, John Berdahl

Abstract readReview
In one paragraph

Review in European journal of ophthalmology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

  1. Review
  2. Review
  3. Article
  4. Review
  5. Quantum biology in ophthalmology.Eye (London, England) · 2024
    Article
  6. Article
  7. Article
  8. Article
  9. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Ethan WaisbergUniversity College Dublin School of Medicine, Dublin, Ireland.ORCID 0000-0001-8999-0212
Joshua OngMichigan Medicine, University of Michigan, Ann Arbor, MI, USA.
Mouayad MasalkhiUniversity College Dublin School of Medicine, Dublin, Ireland.
Phani PaladuguSidney Kimmel Medical College, Thomas Jefferson University, Philadelphia, PA, USA.
Andrew G LeeCenter for Space Medicine, Baylor College of Medicine, Houston, TX, USA.
John BerdahlVance Thompson Vision, Sioux Falls, SD, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The translaminar pressure gradient (TLPG) refers to two forces at the lamina cribosa of the optic nerve: the anteriorly acting intracranial pressure (ICP), and posteriorly-acting intraocular pressure (IOP). It has been proposed that controlling the translaminar pressure gradient at regular intervals may preserve the optic nerve and slow the course of glaucoma. The precisional modulation of this TLPG is a recently introduced concept that may play a role in the treatment of ophthalmic diseases such as glaucoma. In this manuscript, we review the applications of pressurized goggles on ophthalmic diseases. We also elaborate upon current investigations in modulation of the TLPG including goggles and the multi-pressure dial goggle. We discuss future research directions for ophthalmic diseases including spaceflight associated neuro-ocular syndrome (SANS), a large physiological barrier to future long-duration spaceflight.

Indexed as

Intracranial PressureIntraocular PressureGlaucomaHumansSpace Flightglaucomalong-duration spaceflightspaceflight associated neuro-ocular syndromeTranslaminar pressure gradient

Identifiers

PMID37670516
PMCPMC11408950

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.