Evidence map›Paper›PMID 37670428›Full record

ArticleInternational journal of epidemiology2023

Software Application Profile: dynamicLM-a tool for performing dynamic risk prediction using a landmark supermodel for survival data under competing risks.

Anya H Fries, Eunji Choi, Julie T Wu, Justin H Lee, Victoria Y Ding, Robert J Huang, Su-Ying Liang, Heather A Wakelee, Lynne R Wilkens, Iona Cheng and 1 more

Abstract read
In one paragraph

Article in International journal of epidemiology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Anya H FriesQuantitative Sciences Unit, Department of Medicine, Stanford University School of Medicine, Stanford, CA, USA.
Eunji ChoiQuantitative Sciences Unit, Department of Medicine, Stanford University School of Medicine, Stanford, CA, USA.ORCID 0000-0003-1315-1433
Julie T WuDivision of Oncology, Department of Medicine, Stanford University School of Medicine, Stanford, CA, USA.
Justin H LeeQuantitative Sciences Unit, Department of Medicine, Stanford University School of Medicine, Stanford, CA, USA.
Victoria Y DingQuantitative Sciences Unit, Department of Medicine, Stanford University School of Medicine, Stanford, CA, USA.
Robert J HuangDivision of Gastroenterology and Hepatology, Department of Medicine, Stanford University School of Medicine, Stanford, CA, USA.
Su-Ying LiangPalo Alto Medical Foundation Research Institute, Palo Alto Medical Foundation, Palo Alto, CA, USA.
Heather A WakeleeDivision of Oncology, Department of Medicine, Stanford University School of Medicine, Stanford, CA, USA.
Lynne R WilkensCancer Epidemiology Program, University of Hawaii Cancer Center, Honolulu, HI, USA.
Iona ChengDepartment of Epidemiology and Biostatistics, University of California, San Francisco, CA, USA.
Summer S HanQuantitative Sciences Unit, Department of Medicine, Stanford University School of Medicine, Stanford, CA, USA.ORCID 0000-0002-2013-6883

Funding

University of Hawaii Cancer Center CCSGP30CA071789 · NCI · UNIVERSITY OF HAWAII AT MANOA · PI GERTRAUD MASKARINEC · 1996 to 2026
$56.2M
Evaluation of genetic, clinical, and environmental risk factors to establish effective screening strategies for second primary lung cancerR37CA226081 · NCI · STANFORD UNIVERSITY · PI HAN, SUMMER S · 2018 to 2024
$4.3M
Integrating Multiple Electronic Health Records Systems to Improve Lung Cancer OutcomesR01CA282793 · NCI · STANFORD UNIVERSITY · PI Summer S Han · 2023 to 2026
$2.6M
NCI NIH HHS P30 CA071789NCI NIH HHS R01 CA282793NCI NIH HHS R37 CA226081NIH HHS 4R37CA226081
6 · The paper itself

Abstract

motivationProviding a dynamic assessment of prognosis is essential for improved personalized medicine. The landmark model for survival data provides a potentially powerful solution to the dynamic prediction of disease progression. However, a general framework and a flexible implementation of the model that incorporates various outcomes, such as competing events, have been lacking. We present an R package, dynamicLM, a user-friendly tool for the landmark model for the dynamic prediction of survival data under competing risks, which includes various functions for data preparation, model development, prediction and evaluation of predictive performance. IMPLEMENTATION: dynamicLM as an R package. GENERAL FEATURES: The package includes options for incorporating time-varying covariates, capturing time-dependent effects of predictors and fitting a cause-specific landmark model for time-to-event data with or without competing risks. Tools for evaluating the prediction performance include time-dependent area under the ROC curve, Brier Score and calibration. AVAILABILITY: Available on GitHub [https://github.com/thehanlab/dynamicLM].

Indexed as

Models, StatisticalSoftwareHumansPrognosisROC Curvecompeting risksdynamic predictionLandmarkRtime-dependent variables

Identifiers

PMID37670428
PMCPMC10749764

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.