ReviewJournal of anesthesia, analgesia and critical care2023
Intracranial pressure for clinicians: it is not just a number.
Review in Journal of anesthesia, analgesia and critical care, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
26 citing papers in PubMed, 34 citations in OpenAlex.
- Prone Positioning in Neurocritical Care Patients with Invasive Intracranial Pressure Monitoring: A Systematic Review and Meta-analysis.Neurocritical care · 2026Article
- Intracranial Pressure Estimation Using B4C Device: A Systematic Review on the Validation Studies.Neurocritical care · 2026Review
- Time-resolved laser speckle contrast imaging (TR-LSCI) of cerebral blood flow response to intracranial pressure elevation.Journal of biomedical optics · 2026Article
- Prognostic value of the intracerebral hematoma volume-to-cerebrospinal fluid volume ratio in patients with spontaneous basal ganglia hemorrhage undergoing non-surgical treatment.BMC neurology · 2026Article
- Characterization of intracranial pressure variations in ventricular and subarachnoid spaces of the rat brain.Journal of applied physiology (Bethesda, Md. : 1985) · 2026Article
- 3D-Printable, Honeycomb-Inspired Tissue-Like Bioelectrodes for Patient-Specific Neural Interface.Advanced materials (Deerfield Beach, Fla.) · 2026Article
- A noninvasive method for assessing optimal cerebral perfusion pressure.Critical care (London, England) · 2026Observational
- First-in-Human Prospective, Observational, and Comparative Clinical Study of Simultaneous Invasive and Non-Invasive Intracranial Pressure Pulse Wave Monitoring.Sensors (Basel, Switzerland) · 2026Observational
- Time-Resolved Laser Speckle Contrast Imaging (TR-LSCI) of Cerebral Blood Flow Response to Intracranial Pressure Elevation.bioRxiv : the preprint server for biology · 2026Article
- Decision-Making in Neurotrauma: a multidimensional model of cognitive and contextual factors influencing surgical judgment in the acute care setting.Brain & spine · 2026Review
- Multimodal Monitoring in Eclamptic Intracerebral Hemorrhage Complicated by Reversible Cerebral Vasoconstriction Syndrome (RCVS): A Case Report.Case reports in critical care · 2026Article
- Adverse events registration in clinical trial participants with severe acute brain injury: a Delphi consensus study.Acta neurochirurgica · 2025Article
- Deep learning-based model for detection of intracranial waveforms with poor brain compliance in southern Thailand.Acute and critical care · 2025Article
- A Novel Approach to Non-Invasive Intracranial Pressure Wave Monitoring: A Pilot Healthy Brain Study.Sensors (Basel, Switzerland) · 2025Article
- Monro-Kellie 4.0: moving from intracranial pressure to intracranial dynamics.Critical care (London, England) · 2025Review
- Intracranial response to positive end-expiratory pressure is influenced by lung recruitability and gas distribution during mechanical ventilation in acute brain injury patients: a proof-of-concept physiological study.Intensive care medicine experimental · 2025Article
- Prospective comparative clinical trials of novel non-invasive intracranial pressure pulse wave monitoring technologies: preliminary clinical data.Interface focus · 2024Article
- Brain health: A concern for anaesthesiologists and intensivists.European journal of anaesthesiology and intensive care · 2024Review
- Article
- Rheoencephalography: A non-invasive method for neuromonitoring.Journal of electrical bioimpedance · 2024Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 2 institutions in 3 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundInvasive intracranial pressure (ICP) monitoring is a standard practice in severe brain injury cases, where it allows to derive cerebral perfusion pressure (CPP); ICP-tracing can also provide additional information about intracranial dynamics, forecast episodes of intracranial hypertension and set targets for a tailored therapy to prevent secondary brain injury. Nevertheless, controversies about the advantages of an ICP clinical management are still debated.
findingsThis article reviews recent research on ICP to improve the understanding of the topic and uncover the hidden information in this signal that may be useful in clinical practice. Parameters derived from time-domain as well as frequency domain analysis include compensatory reserve, autoregulation estimation, pulse waveform analysis, and behavior of ICP in time. The possibility to predict the outcome and apply a tailored therapy using a personalised perfusion pressure target is also described.
conclusionsICP is a crucial signal to monitor in severely brain injured patients; a bedside computer can empower standard monitoring giving new metrics that may aid in clinical management, establish a personalized therapy, and help to predict the outcome. Continuous collaboration between engineers and clinicians and application of new technologies to healthcare, is vital to improve the accuracy of current metrics and progress towards better care with individualized dynamic targets.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.