Evidence map›Paper›PMID 37670294›Full record

ArticleBMC complementary medicine and therapies2023

The aqueous extract of Artemisia Absinthium L. stimulates HO-1/MT-1/Cyp450 signaling pathway via oxidative stress regulation induced by aluminium oxide nanoparticles (α and γ) animal model.

Esmaeil Karami, Zahra Goodarzi, Seyed Jamaleddin Shahtaheri, Mehrafarin Kiani, Mohammad Faridan, Mahmoud Ghazi-Khansari

Expression of concernOpen access · goldAbstract read
In one paragraph

Article in BMC complementary medicine and therapies, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It carries an expression of concern. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.7field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 3 citations in OpenAlex.

  1. Article
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 1 country.

Esmaeil KaramiDepartment of Occupational Health Engineering, School of Health, Tehran University of Medical Sciences, Tehran, Iran.
Zahra GoodarziDepartment of Occupational Health Engineering, Faculty of Medical Sciences, Tarbiat Modares University, Tehran, Iran.
Seyed Jamaleddin ShahtaheriDepartment of Occupational Health Engineering, School of Health, Tehran University of Medical Sciences, Tehran, Iran. shahtaheri@tums.ac.ir.
Mehrafarin KianiDepartment of Anatomical Sciences, Faculty of Medical Sciences, Tarbiat Modares University, Tehran, Iran.
Mohammad FaridanDepartment of Occupational Health and Safety at Work Engineering, Environmental Health Research CenterLorestan University of Medical Sciences, Khorramabad, Iran.
Mahmoud Ghazi-KhansariDepartment of Pharmacology, School of Medicine, Tehran University of Medical Sciences, Tehran, Iran.
Tehran University of Medical Sciences · IRTarbiat Modares University · IRLorestan University of Medical Sciences · IR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThis research aimed to evaluate the protective effects of Artemisia Absinthium L. (Abs) against liver damage induced by aluminium oxide nanoparticles (Al

methodsThirty-six rats were randomly divided into six groups (n = 6). The first group received no treatment. The second group was orally administered Abs at a dose of 200 mg/kg/b.w. The third and fifth groups were injected intraperitoneally with γ-Al

resultsTreatment with γ-Al

conclusionThe results indicate that Abs has potential protective effects against oxidative stress, up-regulation of oxidative-related genes and proteins, and histopathological alterations induced by Al

Indexed as

Artemisia absinthiumChemical and Drug Induced Liver InjuryAluminum OxideAnimalsBody WeightCytochrome P-450 Enzyme SystemHeme Oxygenase-1Models, AnimalOxidative StressRatsSignal TransductionAluminum OxideCytochrome P-450 Enzyme SystemHeme Oxygenase-1Al2O3 NPsArtemisia Absinthium LGene expressionHistopathologyOxidative stress

Identifiers

PMID37670294
PMCPMC10478434
OpenAlexW4386460853

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.