Evidence map›Paper›PMID 37670273›Full record

ArticleMicrobial cell factories2023

New investigation of anti-inflammatory activity of Polycladia crinita and biosynthesized selenium nanoparticles: isolation and characterization.

Alanood S Almurshedi, Thanaa A El-Masry, Hend Selim, Mostafa M El-Sheekh, Mofida E M Makhlof, Basmah N Aldosari, Iman M Alfagih, Bushra T AlQuadeib, Salma S Almarshidy, Maisra M El-Bouseary

Open access · goldAbstract read
In one paragraph

Article in Microbial cell factories, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
7.9field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 23 citations in OpenAlex.

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  8. New insights into the anticancer effects ofFrontiers in pharmacology · 2024
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 2 countries.

Alanood S Almurshedi *Department of Pharmaceutics, College of Pharmacy, King Saud University, Riyadh, Saudi Arabia.ORCID http://orcid.org/0000-0001-7736-6279
Thanaa A El-MasryDepartment of Pharmacology and Toxicology, Faculty of Pharmacy, Tanta University, Tanta, Egypt.ORCID http://orcid.org/0000-0002-1453-5597
Hend Selim *Department of Biochemistry, Faculty of Pharmacy, Tanta University, Tanta, Egypt. hend.m.selim@pharm.tanta.edu.eg.
Mostafa M El-SheekhBotany Department, Faculty of Science, Tanta University, Tanta, Egypt.
Mofida E M MakhlofBotany and Microbiology Department, Faculty of Science, Damanhour University, Damanhour, Egypt.ORCID http://orcid.org/0000-0002-8636-7430
Basmah N AldosariDepartment of Pharmaceutics, College of Pharmacy, King Saud University, Riyadh, Saudi Arabia.
Iman M AlfagihDepartment of Pharmaceutics, College of Pharmacy, King Saud University, Riyadh, Saudi Arabia.
Bushra T AlQuadeibDepartment of Pharmaceutics, College of Pharmacy, King Saud University, Riyadh, Saudi Arabia.
Salma S AlmarshidyDepartment of Pharmaceutics, College of Pharmacy, King Saud University, Riyadh, Saudi Arabia.
Maisra M El-BousearyDepartment of Pharmaceutical Microbiology, Faculty of Pharmacy, Tanta University, Tanta, Egypt. maysra_mohamed@pharm.tanta.edu.eg.ORCID http://orcid.org/0000-0001-6503-0719
King Saud University · SATanta University · EGDamanhour University · EG

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundMarine macroalgae have gained interest recently, mostly due to their bioactive components. Polycladia crinita is an example of marine macroalgae from the Phaeophyceae class, also known as brown algae. They are characterized by a variety of bioactive compounds with valuable medical applications. The prevalence of such naturally active marine resources has made macroalgae-mediated manufacturing of nanoparticles an appealing strategy. In the present study, we aimed to evaluate the antioxidant and anti-inflammatory features of an aqueous extract of Polycladia crinita and biosynthesized P. crinita selenium nanoparticles (PCSeNPs) via a carrageenan-induced rat paw edema model. The synthesized PCSeNPs were fully characterized by UV-visible spectroscopy, FTIR, XRD, and EDX analyses.

resultsFTIR analysis of Polycladia crinita extract showed several sharp absorption peaks at 3435.2, 1423.5, and 876.4 cm

conclusionsThese distinguishing features imply that this unique alga is a promising anti-inflammatory agent. Further studies are required to investigate its main active ingredients and possible side effects.

Indexed as

NanoparticlesSeaweedSeleniumAnimalsAntibodiesAnti-Inflammatory AgentsAntioxidantsCyclooxygenase 2PyruvatesRatsAntibodiesAnti-Inflammatory AgentsAntioxidantsCyclooxygenase 2PyruvatesSeleniumsulfoenolpyruvateAnti-inflammatoryAnti-oxidantBrown AlgaeCarrageenanMacroalgaePolycladia crinitaSelenium nanoparticles

Identifiers

PMID37670273
PMCPMC10478239
OpenAlexW4386459741

What OpenQuestion holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.