Evidence map›Paper›PMID 37670148›Full record

ReviewNature reviews. Endocrinology2023

Diagnosis and management of prolactin-secreting pituitary adenomas: a Pituitary Society international Consensus Statement.

Stephan Petersenn, Maria Fleseriu, Felipe F Casanueva, Andrea Giustina, Nienke Biermasz, Beverly M K Biller, Marcello Bronstein, Philippe Chanson, Hidenori Fukuoka, Monica Gadelha and 26 more

Erratum issuedOpen access · greenAbstract readReviewConsensus Statement
PubMed Publisher
In one paragraph

Review in Nature reviews. Endocrinology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 223 papers, 8 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
223citing papers in PubMed, 8 pooled it
60.9field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

223 citing papers in PubMed, 8 syntheses or guidelines pooled it, 305 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Pooled it
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  5. Clinical characteristics associated with somaticFrontiers in endocrinology · 2026
    Pooled it
  6. Pooled it
  7. American Association of Clinical Endocrinology Consensus Statement on Management of Multiple Endocrine Neoplasia Type 1.Endocrine practice : official journal of the American College of Endocrinology and the American Association of Clinical Endocrinologists · 2025
    Guideline
  8. Pooled it
  9. Is endoscopic diving technique effective in surgical management of functioning pituitary adenomas? A prospective randomized study.European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery · 2025
    Trial
  10. Observational
  11. Functional pituitary adenoma imaging.Reviews in endocrine & metabolic disorders · 2026
    Review
  12. Article
  13. Review
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  15. Article
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  19. Review
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163 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

36 authors at 20 institutions in 13 countries.

Stephan PetersennENDOC Center for Endocrine Tumors, Hamburg, Germany. stephan.petersenn@endoc-med.de.ORCID 0000-0002-0618-6147
Maria FleseriuOregon Health Sciences University, Portland, OR, USA.ORCID 0000-0001-9284-6289
Felipe F CasanuevaSantiago de Compostela University, Santiago de Compostela, Spain.
Andrea GiustinaSan Raffaele Vita-Salute University, Milan, Italy.
Nienke BiermaszLeiden University Medical Center, Leiden, Netherlands.ORCID 0000-0001-5817-3594
Beverly M K BillerMassachusetts General Hospital, Boston, MA, USA.
Marcello BronsteinHospital das Clinicas, University of Sao Paulo, Sao Paulo, Brazil.
Philippe ChansonUniversité Paris-Saclay, Assistance Publique-Hôpitaux de Paris Hôpital Bicêtre, Le Kremlin-Bicêtre, France.
Hidenori FukuokaKobe University Hospital, Kobe, Hyogo, Japan.ORCID 0000-0001-9255-653X
Monica GadelhaUniversidade Federal do Rio de Janeiro, Rio de Janeiro, Brazil.
Yona GreenmanTel Aviv-Sourasky Medical Center, Tel Aviv, Israel.ORCID 0000-0003-4923-488X
Mark GurnellUniversity of Cambridge, Cambridge, UK.
Ken K Y HoGarvan Institute of Medical Research, Sydney, New South Wales, Australia.ORCID 0000-0002-2508-9588
Jürgen HoneggerUniversity of Tübingen, Tübingen, Germany.
Adriana G IoachimescuMedical College of Wisconsin, Milwaukee, WI, USA.
Ursula B KaiserBrigham and Women's Hospital and Harvard Medical School, Boston, MA, USA.
Niki KaravitakiInstitute of Metabolism and Systems Research, College of Medical and Dental Sciences, University of Birmingham, Birmingham, UK.ORCID 0000-0002-4696-0643
Laurence KatznelsonStanford University School of Medicine, Stanford, CA, USA.
Maya LodishUniversity of California, San Francisco, San Francisco, CA, USA.
Dominique MaiterUCLouvain Cliniques Universitaires Saint Luc, Brussels, Belgium.ORCID 0000-0002-0918-637X
Hani J MarcusNational Hospital for Neurology and Neurosurgery, University College London Hospitals NHS Foundation Trust, London, UK.
Ann McCormackGarvan Institute of Medical Research, Sydney, New South Wales, Australia.
Mark MolitchNorthwestern University Feinberg School of Medicine, Chicago, IL, USA.
Christopher A MuirSt Vincent's Hospital, Sydney, New South Wales, Australia.
Sebastian NeggersErasmus University Medical Centre, Rotterdam, Netherlands.
Alberto M PereiraAmsterdam University Medical Centre, University of Amsterdam, Amsterdam, Netherlands.ORCID 0000-0002-1194-9866
Rosario PivonelloUniversità Federico II Di Napoli, Naples, Italy.ORCID 0000-0002-9632-1348
Kalmon PostMount Sinai Health System, New York, NY, USA.
Gerald RaverotDepartment of Endocrinology, Reference Centre for Rare Pituitary Diseases HYPO, "Groupement Hospitalier Est" Hospices Civils de Lyon, Bron, France.ORCID 0000-0002-9517-338X
Roberto SalvatoriJohns Hopkins University, Baltimore, MD, USA.ORCID 0000-0001-6495-2244
Susan L SamsonMayo Clinic, Jacksonville, FL, USA.
Ilan ShimonTel Aviv University, Tel Aviv, Israel.
Joanna Spencer-SegalUniversity of Michigan, Ann Arbor, MI, USA.
Greisa VilaMedical University of Vienna, Vienna, Austria.ORCID 0000-0003-1918-1959
John WassUniversity of Oxford, Oxford, UK.
Shlomo MelmedCedars-Sinai Medical Center, Los Angeles, CA, USA.ORCID 0000-0002-2355-3447
Garvan Institute of Medical Research · AUTel Aviv University · ILBrigham and Women's Hospital · USCedars-Sinai Medical Center · USChurchill Hospital · GBCliniques Universitaires Saint-Luc · BEErasmus University Rotterdam · NLHospices Civils de Lyon · FRHospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo · BRJohns Hopkins University · USKobe University Hospital · JPLeiden University Medical Center · NLMassachusetts General Hospital · USMedical College of Wisconsin · USMedical University of Vienna · ATMount Sinai Health System · USNorthwestern University · USOregon Health & Science University · USStanford University · USSt Vincent's Hospital Sydney · AU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This Consensus Statement from an international, multidisciplinary workshop sponsored by the Pituitary Society offers evidence-based graded consensus recommendations and key summary points for clinical practice on the diagnosis and management of prolactinomas. Epidemiology and pathogenesis, clinical presentation of disordered pituitary hormone secretion, assessment of hyperprolactinaemia and biochemical evaluation, optimal use of imaging strategies and disease-related complications are addressed. In-depth discussions present the latest evidence on treatment of prolactinoma, including efficacy, adverse effects and options for withdrawal of dopamine agonist therapy, as well as indications for surgery, preoperative medical therapy and radiation therapy. Management of prolactinoma in special situations is discussed, including cystic lesions, mixed growth hormone-secreting and prolactin-secreting adenomas and giant and aggressive prolactinomas. Furthermore, considerations for pregnancy and fertility are outlined, as well as management of prolactinomas in children and adolescents, patients with an underlying psychiatric disorder, postmenopausal women, transgender individuals and patients with chronic kidney disease. The workshop concluded that, although treatment resistance is rare, there is a need for additional therapeutic options to address clinical challenges in treating these patients and a need to facilitate international registries to enable risk stratification and optimization of therapeutic strategies.

Indexed as

HyperprolactinemiaPituitary NeoplasmsProlactinomaAdolescentChildDiagnostic ImagingDopamine AgonistsFemaleHumansPregnancyProlactinDopamine AgonistsProlactin

Identifiers

PMID37670148
OpenAlexW4386449135

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.