SynthesisJournal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract2023
Duodenum-Preserving Pancreatic Head Resection for Benign and Premalignant Tumors-a Systematic Review and Meta-analysis of Surgery-Associated Morbidity.
Synthesis in Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 2 of them syntheses that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
14 citing papers in PubMed, 2 syntheses or guidelines pooled it, 15 citations in OpenAlex.
- Laparoscopic duodenum-preserving pancreatic head resection in 459 patients for precancerous, cystic neoplasms, and neuroendocrine tumors. Perioperative outcome: systematic review and meta-analysis.Surgical endoscopy · 2026Pooled it
- Long-Term Oncologic Outcome following Duodenum-Preserving Pancreatic Head Resection for Benign Tumors, Cystic Neoplasms, and Neuroendocrine Tumors: Systematic Review and Meta-analysis.Annals of surgical oncology · 2024Pooled it
- Learning curve of laparoscopic duodenum-preserving total pancreatic head resection: a single-center dual CUSUM and risk-adjusted CUSUM analysis.Surgical endoscopy · 2026Article
- Uncertainty-Aware Explainable AI for Pancreatic Cysts: Identifying Deep Learning Vulnerabilities and Ensuring Safe Clinical Triage in IPMN Management.Research square · 2026Article
- Laparoscopic duodenum-preserving total pancreatic head resection for benign and low-grade malignant tumors close to the accessory papilla (a case series).Surgical endoscopy · 2026Article
- Evolution and precision trends of pancreaticojejunostomy in pancreaticoduodenectomy.Frontiers in oncology · 2026Review
- Risk factors for postoperative outcomes in laparoscopic pancreaticoduodenectomy: a retrospective cohort study from 2015 to 2023.Gland surgery · 2025Article
- The value of a nomogram model based on CT imaging features in differentiating duodenal gastrointestinal stromal tumors from pancreatic head neuroendocrine tumors.Abdominal radiology (New York) · 2025Article
- Pathological diagnosis and clinical feature analysis of descending duodenal mucosal adenocarcinoma: A case report.World journal of gastrointestinal surgery · 2024Article
- The efficacy and safety of single-incision plus one-port laparoscopic surgeryGland surgery · 2024Article
- [Premalignant cystic neoplasms and neuroendocrine tumors of the pancreatic head-Is the Kausch-Whipple resection an adequate treatment?]Chirurgie (Heidelberg, Germany) · 2024Review
- Novel Insights into Postoperative Surveillance in Resected Pancreatic Cystic Neoplasms-A Review.Diagnostics (Basel, Switzerland) · 2024Review
- Article
- Pancreatic neuroendocrine tumors - going beyond surgery. Literature review and experience of a tertiary center.Romanian journal of morphology and embryology = Revue roumaine de morphologie et embryologieReview
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Authors and funding
3 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundPancreatic benign, cystic, and neuroendocrine neoplasms are increasingly detected and recommended for surgical treatment. In multiorgan resection pancreatoduodenectomy or parenchyma-sparing, local extirpation is a challenge for decision-making regarding surgery-related early and late postoperative morbidity.
methodsPubMed, Embase, and Cochrane Libraries were searched for studies reporting early surgery-related complications following pancreatoduodenectomy (PD) and duodenum-preserving total (DPPHRt) or partial (DPPHRp) pancreatic head resection for benign tumors. Thirty-four cohort studies comprising data from 1099 patients were analyzed. In total, 654 patients underwent DPPHR and 445 patients PD for benign tumors. This review and meta-analysis does not need ethical approval.
resultsComparing DPPHRt and PD, the need for blood transfusion (OR 0.20, 95% CI 0.10-0.41, p<0.01), re-intervention for serious surgery-related complications (OR 0.48, 95% CI 0.31-0.73, p<0.001), and re-operation for severe complications (OR 0.50, 95% CI 0.26-0.95, p=0.04) were significantly less frequent following DPPHRt. Pancreatic fistula B+C (19.0 to 15.3%, p=0.99) and biliary fistula (6.3 to 4.3%; p=0.33) were in the same range following PD and DPPHRt. In-hospital mortality after DPPHRt was one of 350 patients (0.28%) and after PD eight of 445 patients (1.79%) (OR 0.32, 95% CI 0.10-1.09, p=0.07). Following DPPHRp, there was no mortality among the 192 patients.
conclusionDPPHR for benign pancreatic tumors is associated with significantly fewer surgery-related, serious, and severe postoperative complications and lower in-hospital mortality compared to PD. Tailored use of DPPHRt or DPPHRp contributes to a reduction of surgery-related complications. DPPHR has the potential to replace PD for benign tumors and premalignant cystic and neuroendocrine neoplasms of the pancreatic head.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.