Evidence map›Paper›PMID 37670066›Full record

ArticleScientific reports2023

OCT-based deep-learning models for the identification of retinal key signs.

Inferrera Leandro, Borsatti Lorenzo, Miladinovic Aleksandar, Marangoni Dario, Giglio Rosa, Accardo Agostino, Tognetto Daniele

Open access · goldAbstract read
In one paragraph

Article in Scientific reports, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed, 1 pooled it
10.1field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

25 citing papers in PubMed, 1 synthesis or guideline pooled it, 44 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Inferrera Leandro *Department of Medicine, Surgery and Health Sciences, Eye Clinic, Ophthalmology Clinic, University of Trieste, Piazza Dell'Ospitale 1, 34125, Trieste, Italy. leandro.inferrera@units.it.
Borsatti Lorenzo *Department of Medicine, Surgery and Health Sciences, Eye Clinic, Ophthalmology Clinic, University of Trieste, Piazza Dell'Ospitale 1, 34125, Trieste, Italy.
Miladinovic Aleksandar *Institute for Maternal and Child Health IRCCS "Burlo Garofolo", Trieste, Italy.
Marangoni DarioDepartment of Medicine, Surgery and Health Sciences, Eye Clinic, Ophthalmology Clinic, University of Trieste, Piazza Dell'Ospitale 1, 34125, Trieste, Italy.
Giglio RosaDepartment of Medicine, Surgery and Health Sciences, Eye Clinic, Ophthalmology Clinic, University of Trieste, Piazza Dell'Ospitale 1, 34125, Trieste, Italy.
Accardo AgostinoDepartment of Engineering and Architecture, University of Trieste, Trieste, Italy.
Tognetto DanieleDepartment of Medicine, Surgery and Health Sciences, Eye Clinic, Ophthalmology Clinic, University of Trieste, Piazza Dell'Ospitale 1, 34125, Trieste, Italy.
University of Trieste · ITIRCCS Materno Infantile Burlo Garofolo · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A new system based on binary Deep Learning (DL) convolutional neural networks has been developed to recognize specific retinal abnormality signs on Optical Coherence Tomography (OCT) images useful for clinical practice. Images from the local hospital database were retrospectively selected from 2017 to 2022. Images were labeled by two retinal specialists and included central fovea cross-section OCTs. Nine models were developed using the Visual Geometry Group 16 architecture to distinguish healthy versus abnormal retinas and to identify eight different retinal abnormality signs. A total of 21,500 OCT images were screened, and 10,770 central fovea cross-section OCTs were included in the study. The system achieved high accuracy in identifying healthy retinas and specific pathological signs, ranging from 93 to 99%. Accurately detecting abnormal retinal signs from OCT images is crucial for patient care. This study aimed to identify specific signs related to retinal pathologies, aiding ophthalmologists in diagnosis. The high-accuracy system identified healthy retinas and pathological signs, making it a useful diagnostic aid. Labelled OCT images remain a challenge, but our approach reduces dataset creation time and shows DL models' potential to improve ocular pathology diagnosis and clinical decision-making.

Indexed as

Deep LearningTomography, Optical CoherenceFovea CentralisHumansRetinaRetrospective Studies

Identifiers

PMID37670066
PMCPMC10480174
OpenAlexW4386443378

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.