Evidence map›Paper›PMID 37669977›Full record

ArticleNature communications2023

A deep learning-based stripe self-correction method for stitched microscopic images.

Shu Wang, Xiaoxiang Liu, Yueying Li, Xinquan Sun, Qi Li, Yinhua She, Yixuan Xu, Xingxin Huang, Ruolan Lin, Deyong Kang and 5 more

Abstract read
In one paragraph

Article in Nature communications, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
  4. Article
  5. Article
  6. Article
  7. Improving the U-Net Configuration for Automated Delineation of Head and Neck Cancer on MRI.Head and Neck Tumor Segmentation for MR-Guided Applications : First MICCAI Challenge, HNTS-MRG 2024, held in conjunction with MICCAI 2024, Marrakesh, Morocco, October 17, 2024, proceedings · 2025
    Article
  8. Review
  9. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Shu Wang *College of Mechanical Engineering and Automation, Fuzhou University, Fuzhou, 350108, China.ORCID http://orcid.org/0000-0003-0829-5694
Xiaoxiang Liu *College of Computer and Data Science, Fuzhou University, Fuzhou, 350108, China.
Yueying Li *College of Mechanical Engineering and Automation, Fuzhou University, Fuzhou, 350108, China.
Xinquan SunCollege of Mechanical Engineering and Automation, Fuzhou University, Fuzhou, 350108, China.
Qi LiCollege of Computer and Data Science, Fuzhou University, Fuzhou, 350108, China.
Yinhua SheCollege of Computer and Data Science, Fuzhou University, Fuzhou, 350108, China.
Yixuan XuCollege of Mechanical Engineering and Automation, Fuzhou University, Fuzhou, 350108, China.
Xingxin HuangKey Laboratory of OptoElectronic Science and Technology for Medicine of Ministry of Education, Fujian Provincial Key Laboratory of Photonics Technology, Fujian Normal University, Fuzhou, 350007, China.
Ruolan LinDepartment of Radiology, Fujian Medical University Union Hospital, Fuzhou, 350001, China.
Deyong KangDepartment of Pathology, Fujian Medical University Union Hospital, Fuzhou, 350001, China.
Xingfu WangDepartment of Pathology, The First Affiliated Hospital of Fujian Medical University, Fuzhou, 350005, China.
Haohua TuBeckman Institute for Advanced Science and Technology, University of Illinois at Urbana-Champaign, Urbana, IL, 61801, USA.
Wenxi LiuCollege of Computer and Data Science, Fuzhou University, Fuzhou, 350108, China. wenxiliu@fzu.edu.cn.ORCID http://orcid.org/0000-0002-3630-6322
Feng HuangCollege of Mechanical Engineering and Automation, Fuzhou University, Fuzhou, 350108, China. huangf@fzu.edu.cn.ORCID http://orcid.org/0000-0003-4652-4312
Jianxin ChenKey Laboratory of OptoElectronic Science and Technology for Medicine of Ministry of Education, Fujian Provincial Key Laboratory of Photonics Technology, Fujian Normal University, Fuzhou, 350007, China. chenjianxin@fjnu.edu.cn.ORCID http://orcid.org/0000-0001-8519-4462

Funding

National Natural Science Foundation of China (National Science Foundation of China) 82171991Natural Science Foundation of Fujian Province (Fujian Provincial Natural Science Foundation) 2022J01216
6 · The paper itself

Abstract

Stitched fluorescence microscope images inevitably exist in various types of stripes or artifacts caused by uncertain factors such as optical devices or specimens, which severely affects the image quality and downstream quantitative analysis. Here, we present a deep learning-based Stripe Self-Correction method, so-called SSCOR. Specifically, we propose a proximity sampling scheme and adversarial reciprocal self-training paradigm that enable SSCOR to utilize stripe-free patches sampled from the stitched microscope image itself to correct their adjacent stripe patches. Comparing to off-the-shelf approaches, SSCOR can not only adaptively correct non-uniform, oblique, and grid stripes, but also remove scanning, bubble, and out-of-focus artifacts, achieving the state-of-the-art performance across different imaging conditions and modalities. Moreover, SSCOR does not require any physical parameter estimation, patch-wise manual annotation, or raw stitched information in the correction process. This provides an intelligent prior-free image restoration solution for microscopists or even microscope companies, thus ensuring more precise biomedical applications for researchers.

Identifiers

PMID37669977
PMCPMC10480181

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.