Evidence map›Paper›PMID 37669361›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America2023

Reframing quercetin as a promiscuous inhibitor against SARS-CoV-2 main protease.

Haohao Yan, Rui Zhang, Xiaoping Liu, Yanchang Wang, Yunyu Chen

Abstract readLetter
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. In vitro enzymatic assays invalidate dihydromyricetin as a potential inhibitor against enterovirus A71 3C protease: beware of fluorescence quenching artifacts.Medicinal chemistry research : an international journal for rapid communications on design and mechanisms of action of biologically active agents · 2026
    Article
  2. Article
  3. Article
  4. Reply to Yan et al.: Quercetin possesses a fluorescence quenching effect but is a weak inhibitor against SARS-CoV-2 main protease.Proceedings of the National Academy of Sciences of the United States of America · 2023
    Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

5 authors.

Haohao Yan *Institute for Drug Screening and Evaluation, Wannan Medical College, Wuhu 241002, China.
Rui Zhang *Institute for Drug Screening and Evaluation, Wannan Medical College, Wuhu 241002, China.
Xiaoping LiuInstitute for Drug Screening and Evaluation, Wannan Medical College, Wuhu 241002, China.
Yanchang WangDepartment of Biomedical Sciences, College of Medicine, Florida State University, Tallahassee, FL 32306.ORCID 0000-0001-6782-0570
Yunyu ChenInstitute for Drug Screening and Evaluation, Wannan Medical College, Wuhu 241002, China.ORCID 0000-0002-2750-8221

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

COVID-19QuercetinCoronavirus 3C ProteasesHumansSARS-CoV-23C-like proteinase, SARS-CoV-2Coronavirus 3C ProteasesQuercetin

Identifiers

PMID37669361
PMCPMC10500161

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.