Evidence map›Paper›PMID 37669289›Full record

ArticlePloS one2023

Evaluating the effectiveness and cost-effectiveness of a digital, app-based intervention for depression (VMood) in community-based settings in Vietnam: Protocol for a stepped-wedge randomized controlled trial.

Leena W Chau, Jill K Murphy, Vu Cong Nguyen, Hui Xie, Raymond W Lam, Harry Minas, Yufei Zheng, Emanuel Krebs, Kanna Hayashi, Son Dao and 4 more

Registry-linked trialAbstract readClinical Trial Protocol
In one paragraph

Article in PloS one, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05783531 (AIMDiV), which is not on this map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05783531 naunknown statusnot on this map

AIMDiV: Accessing Innovative Mental Health Services for Depression in Vietnam

TypeinterventionalSponsorSimon Fraser UniversityRan2023 to 2026Enrolled336ConditionsDepression, Anxiety DisordersArmsVMood, Enhanced treatment as usual
3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Leena W ChauFaculty of Health Sciences, Simon Fraser University, Vancouver, Canada.ORCID 0000-0001-8557-3542
Jill K MurphyFaculty of Medicine, Department of Psychiatry, The University of British Columbia, Vancouver, Canada.
Vu Cong NguyenInstitute of Population, Health and Development, Hanoi, Vietnam.
Hui XieFaculty of Health Sciences, Simon Fraser University, Vancouver, Canada.
Raymond W LamFaculty of Medicine, Department of Psychiatry, The University of British Columbia, Vancouver, Canada.
Harry MinasGlobal and Cultural Mental Health Unit, Centre for Mental Health, Melbourne School of Population and Global Health, University of Melbourne, Melbourne, Australia.ORCID 0000-0003-1719-7367
Yufei ZhengFaculty of Health Sciences, Simon Fraser University, Vancouver, Canada.
Emanuel KrebsFaculty of Health Sciences, Simon Fraser University, Vancouver, Canada.
Kanna HayashiFaculty of Health Sciences, Simon Fraser University, Vancouver, Canada.ORCID 0000-0003-3843-2928
Son DaoInstitute of Population, Health and Development, Hanoi, Vietnam.
Xuan NguyenInstitute of Population, Health and Development, Hanoi, Vietnam.
Viet Anh DuongInstitute of Population, Health and Development, Hanoi, Vietnam.
Eugene FiumeFaculty of Applied Sciences, Simon Fraser University, Vancouver, Canada.ORCID 0000-0001-5939-7055
John O'NeilFaculty of Health Sciences, Simon Fraser University, Vancouver, Canada.

Funding

CIHR PJT 178156
6 · The paper itself

Abstract

The COVID-19 pandemic has amplified mental health problems and highlighted inequitable gaps in care worldwide. In response there has been an explosion of digital interventions such as smartphone applications ("apps") to extend care. The objective of this trial is to evaluate the effectiveness and cost-effectiveness of a digital depression intervention (VMood), delivered via a smartphone app. VMood is adapted from an in-person intervention that was delivered by non-specialist providers and shown to be effective in the Vietnamese context in our previous trial (2016-2019). A stepped-wedge, randomized controlled trial will be conducted across eight provinces in Vietnam. Adults aged 18 years and over will be recruited through community-based primary care centres and screened for depression using the embedded Patient Health Questionnaire-9 (primary outcome measure). Participants scoring 10-19, indicating depression caseness, will be randomly allocated to the intervention or control group until the target of 336 is reached. Secondary outcome measures will examine the effect of the intervention on commonly co-occuring anxiety, quality of life and work productivity, along with use of alcohol and tobacco products. Assessments will be administered through an online survey platform (REDCap) at baseline, and at every 3 months until 3 months post-intervention. Intervention-group participants will receive VMood for a 3-month period, with online support provided by social workers. Control-group participants will receive a limited version of the app until they cross into the intervention group. Generalized Linear Mixed-effect Models for clustered measures will be used for all outcomes data. We will conduct a cost-effectiveness analysis alongside the trial to capture VMood's costs and benefits. This trial will provide evidence on the effectiveness and cost-effectiveness of a digital mental health intervention adapted from an in-person intervention. This trial will also contribute important information to the growing and promising field of digital mental health. Trail regulation. Registered at ClinicalTrials.gov, identifier [NCT05783531].

Indexed as

COVID-19Mobile ApplicationsAdolescentAdultCost-Benefit AnalysisDepressionHumansPandemicsQuality of LifeRandomized Controlled Trials as TopicVietnam

Identifiers

PMID37669289
PMCPMC10479903

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.