Evidence map›Paper›PMID 37669145›Full record

ArticleACS nano2023

Guanidyl-Rich Poly(β Amino Ester)s for Universal Functional Cytosolic Protein Delivery and Clustered Regularly Interspaced Short Palindromic Repeats (CRISPR) Cas9 Ribonucleoprotein Based Gene Editing.

Xianqing Wang, Yinghao Li, Xi Wang, Dario M Sandoval, Zhonglei He, Sigen A, Irene Lara Sáez, Wenxin Wang

Open access · hybridAbstract read
In one paragraph

Article in ACS nano, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
4.5field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 29 citations in OpenAlex.

  1. Article
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  9. CRISPR-Cas9 applications in T cells and adoptive T cell therapies.Cellular & molecular biology letters · 2024
    Review
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  11. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 2 countries.

Xianqing WangCharles Institute of Dermatology, School of Medicine, University College Dublin, D04 V1W8 Dublin, Ireland.
Yinghao LiCharles Institute of Dermatology, School of Medicine, University College Dublin, D04 V1W8 Dublin, Ireland.
Xi WangResearch and Clinical Translation Center of Gene Medicine and Tissue Engineering, School of Public Health, Anhui University of Science and Technology, Huainan 232001, China.
Dario M SandovalCharles Institute of Dermatology, School of Medicine, University College Dublin, D04 V1W8 Dublin, Ireland.
Zhonglei HeCharles Institute of Dermatology, School of Medicine, University College Dublin, D04 V1W8 Dublin, Ireland.
Sigen ACharles Institute of Dermatology, School of Medicine, University College Dublin, D04 V1W8 Dublin, Ireland.
Irene Lara SáezCharles Institute of Dermatology, School of Medicine, University College Dublin, D04 V1W8 Dublin, Ireland.
Wenxin WangCharles Institute of Dermatology, School of Medicine, University College Dublin, D04 V1W8 Dublin, Ireland.ORCID 0000-0002-5053-0611
University College Dublin · IE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Protein therapeutics are highly promising for complex disease treatment. However, the lack of ideal delivery vectors impedes their clinical use, especially the carriers for

Indexed as

CRISPR-Cas SystemsGene EditingEstersGreen Fluorescent ProteinsGuanidineGuanidinesHeLa CellsHumansPolymersEstersGreen Fluorescent ProteinsGuanidineGuanidinespoly(beta-amino ester)PolymersCRISPR/Cas9 ribonucleoprotein transfectioncytosolic protein deliverygene editingguanidylpoly(β amino ester)s

Identifiers

PMID37669145
PMCPMC10540258
OpenAlexW4386461857

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.