Observational studyInvestigative ophthalmology & visual science2023
Longitudinal Changes in Axial Length and Spherical Equivalent in Children and Adolescents With High Myopia.
Observational study in Investigative ophthalmology & visual science, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 3 of them syntheses that pooled it.
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
20 citing papers in PubMed, 3 syntheses or guidelines pooled it, 20 citations in OpenAlex.
- Prevalence of myopia in Chinese children and adolescents: a systematic review and meta-analysis.Journal of global health · 2026Pooled it
- Repeated low-level red-light therapy vs. conventional treatments for myopic control in children: a systematic review and meta-analysis.Scientific reports · 2025Pooled it
- Myopia progression after cessation of atropine in children: a systematic review and meta-analysis.Frontiers in pharmacology · 2024Pooled it
- Axial Length to Corneal Curvature Ratio is Insufficient for Detecting Pseudomyopia in Children: A Multi-Cohort Study.Ophthalmic & physiological optics : the journal of the British College of Ophthalmic Opticians (Optometrists) · 2026Article
- Relationships of Body Composition with Refractive Error and Axial Length in 8-Year-Old Japanese Children.Journal of clinical medicine · 2026Article
- The Effect of Three-Dimensional Ocular Shape on Longitudinal Biometric Changes: A Six-Year Follow-Up Study.Translational vision science & technology · 2026Article
- The effects of lutein, zeaxanthin and anthocyanins supplementation on visual function and vision protection in healthy school-aged children: a single-center prospective randomized controlled study.Journal of clinical biochemistry and nutrition · 2026Article
- Correlation between Baseline Axial Length and Myopia Progression Rate in Childhood.Korean journal of ophthalmology : KJO · 2026Article
- Refractive status, visual behaviour, and parental myopia in Portuguese schoolchildren and adolescents.BMC pediatrics · 2026Article
- Vitreous chamber depth as part of axial elongation in pediatric myopia.BMC ophthalmology · 2026Article
- Choroidal structural and perfusion characteristics across refractive groups in children.Frontiers in medicine · 2026Article
- Application of spot vision screening combined with axial length measurement for early identification of myopia risk in Chinese Young children.Frontiers in pediatrics · 2026Article
- Ocular biometric characteristics in young Saudi adults across varying degrees of myopia.PeerJ · 2026Article
- Predictive Utility of Genetic Risk for Myopic Maculopathy Presence and Progression in a Chinese High Myopia Cohort.Investigative ophthalmology & visual science · 2025Article
- Intraocular Pressure Trends in Children with Myopia Receiving Atropine Therapy.Ophthalmology and therapy · 2025Article
- School-level prediction and management of myopia in children and adolescents.Journal of translational medicine · 2025Article
- Visual related quality of life after ICL V4c implantation in high myopia patients: a mini review.Frontiers in medicine · 2025Review
- Clinical advantages of multifocal soft contact lenses in myopia control for adolescents.American journal of translational research · 2025Article
- Comparison of axial length and anterior segment parameters of patients with myopia measured using 2 fourier-domain optical coherent biometry devices.BMC ophthalmology · 2024Article
- Prevalence of myopia and refractive parameters among children and adolescents in Hi-tech District of Chengdu City.Frontiers in pediatrics · 2024Article
Corrections and comments
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Authors and funding
5 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Purpose: To investigate longitudinal changes in axial length (AL) and spherical equivalent (SE) in children and adolescents with high myopia and to explore associated risk factors. Methods: This was a longitudinal, observational cohort study of highly myopic participants (aged 7-17 years) to evaluate the mean rates of change in AL and SE. Mixed effects regression models were used to explore the risk factors. Results: The sample consisted of 293 participants (mean age at the baseline, 13.63 ± 2.66 years; mean AL, 27.03 ± 1.30 mm diopters; mean SE, -8.99 ± 2.30 diopters) who were followed for 7.09 ± 1.64 years. Pathological myopia (PM) was present in 11.95% of the participants at the baseline. Over the follow-up period, the mean AL and SE progression rates were 0.13 mm/y (95% CI, 0.12-0.14) and -0.36 diopters/y (95% CI, -0.39 to -0.34). The multivariate analysis showed that the AL elongation and myopic SE progression decreased significantly after age 11 (β = -0.080, P < 0.001; β = 0.146, P < 0.001), increased with a greater baseline SE (β = -0.006, P = 0.014; β = 0.017, P = 0.005), and accelerated in children and adolescents who had PM at the baseline (β = 0.043, P = 0.011; β = -0.097, P = 0.025). Conclusions: A significant association was found between acceleration of AL elongation and myopic SE progression among the children and adolescents with age, especially those younger than 11 years, and the presence of PM.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.