Evidence map›Paper›PMID 37669003›Full record

Observational studyThe oncologist2024

Elements of End-of-Life Discussions Associated With Patients' Reported Outcomes and Actual End-of-Life Care in Patients With Pretreated Lung Cancer.

Takaaki Hasegawa, Toru Okuyama, Takehiro Uemura, Yoshinobu Matsuda, Hiroyuki Otani, Junichi Shimizu, Yoshitsugu Horio, Naohiro Watanabe, Teppei Yamaguchi, Satoshi Fukuda and 6 more

Open access · goldAbstract readObservational Study
PubMed Full text at PMC Publisher
In one paragraph

Observational study in The oncologist, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
1.2field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 4 citations in OpenAlex.

  1. Unrealistic expectations and disclosure of incurability in patients with non-small cell lung cancer.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2024
    Article
  2. Review
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors at 6 institutions in 1 country.

Takaaki HasegawaCenter for Psycho-oncology and Palliative Care, Nagoya City University Hospital, Nagoya, Aichi, Japan.ORCID 0000-0001-7894-4528
Toru OkuyamaCenter for Psycho-oncology and Palliative Care, Nagoya City University Hospital, Nagoya, Aichi, Japan.ORCID 0000-0003-0504-6406
Takehiro UemuraDepartment of Respiratory Medicine, Allergy and Clinical Immunology, Nagoya City University Graduate School of Medical Sciences, Nagoya, Aichi, Japan.
Yoshinobu MatsudaDepartment of Psychosomatic Internal Medicine, National Hospital Organization, Kinki-Chuo Chest Medical Center, Sakai, Osaka, Japan.ORCID 0000-0001-5092-9377
Hiroyuki OtaniDepartment of Palliative Care Team, Palliative and Supportive Care, National Hospital Organization Kyushu Cancer Center, Fukuoka, Fukuoka, Japan.
Junichi ShimizuDepartment of Thoracic Oncology, Aichi Cancer Center Hospital, Nagoya, Aichi, Japan.
Yoshitsugu HorioDepartment of Thoracic Oncology, Aichi Cancer Center Hospital, Nagoya, Aichi, Japan.
Naohiro WatanabeDepartment of Thoracic Oncology, Aichi Cancer Center Hospital, Nagoya, Aichi, Japan.
Teppei YamaguchiDepartment of Thoracic Oncology, Aichi Cancer Center Hospital, Nagoya, Aichi, Japan.
Satoshi FukudaDepartment of Respiratory Medicine, Allergy and Clinical Immunology, Nagoya City University Graduate School of Medical Sciences, Nagoya, Aichi, Japan.
Tetsuya OguriDepartment of Respiratory Medicine, Allergy and Clinical Immunology, Nagoya City University Graduate School of Medical Sciences, Nagoya, Aichi, Japan.
Ken MaenoDepartment of Respiratory Medicine, Allergy and Clinical Immunology, Nagoya City University Graduate School of Medical Sciences, Nagoya, Aichi, Japan.
Yoshihiko TaniguchiDepartment of Internal Medicine, National Hospital Organization, Kinki-Chuo Chest Medical Center, Sakai, Osaka, Japan.
Kaname NosakiDepartment of Thoracic Oncology, National Hospital Organization Kyushu Cancer Center, Fukuoka, Fukuoka, Japan.
Kensuke FukumitsuDepartment of Respiratory Medicine, Allergy and Clinical Immunology, Nagoya City University Graduate School of Medical Sciences, Nagoya, Aichi, Japan.
Tatsuo AkechiCenter for Psycho-oncology and Palliative Care, Nagoya City University Hospital, Nagoya, Aichi, Japan.ORCID 0000-0003-1100-7518
Nagoya City University · JPAichi Cancer Center · JPNHO Kinki Chuo Chest Medical Center · JPNagoya University Hospital · JPNational Hospital Organization Kyushu Cancer Center · JPSt Mary's Hospital · JP

Funding

Japanese Society for the Promotion of Science, Japan 16K08878
6 · The paper itself

Abstract

backgroundEnd-of-life discussions for patients with advanced cancer are internationally recommended to ensure consistency of end-of-life care with patients' values. This study examined the elements of end-of-life discussions associated with end-of-life care. MATERIALS AND

methodsWe performed a prospective observational study among consecutive patients with pretreated non-small cell lung cancer after the failure of first-line chemotherapy. We asked oncologists whether they had ever discussed "prognosis," "do not attempt resuscitation," "hospice," and "preferred place of death" with a patient at baseline. The quality of life (QOL) and depressive symptoms of patients were assessed using validated questionnaires at baseline and 3 months later. The end-of-life care that patients received was investigated using medical records. Oncologists' compassion and caregivers' preferences for hospice care were also assessed using questionnaires. Multiple regression analyses were conducted to examine the association between elements of end-of-life discussions and patient-reported outcomes as well as actual end-of-life care.

resultsWe obtained 200 valid responses at baseline, 147 valid responses 3 months later, and 145 data points for medical care at the end-of-life stage. No element of the end-of-life discussion between the patient and their oncologist was significantly associated with patients' reported outcomes or actual end-of-life care. In addition, oncologists' compassion was significantly associated with improvement in both comprehensive QOL and depressive symptoms, and caregivers' preferences for hospice care and high educational level were significantly associated with hospice death.

conclusionOncologist-patient alliances and caregivers' involvement in end-of-life discussions may be influential in achieving optimal end-of-life care.

Indexed as

Carcinoma, Non-Small-Cell LungHospice CareLung NeoplasmsNeoplasmsTerminal CareDeathHumansProspective StudiesQuality of Lifeadvance care planningcommunicationend-of-life discussionlung cancerneoplasmpalliative care

Identifiers

PMID37669003
PMCPMC10836313
OpenAlexW4386437705

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.