Evidence map›Paper›PMID 37668901›Full record

ArticleJournal of ultrasound2024

Passive leg raising test using the carotid flow velocity-time integral to predict fluid responsiveness.

Issac Cheong, Victoria Otero Castro, Fernando Ariel Sosa, Bárbara Tort Oribe, María Florencia Früchtenicht, Francisco Marcelo Tamagnone, Pablo Martín Merlo

2 registry-linked trialsOpen access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of ultrasound, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
2.9field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT07245485 completednot on this mapstarted 2025, after this paper: background citation

Fluid Responsiveness in Coronary Artery Bypass Surgery: The Role of Carotid Artery Ultrasound and Passive Leg Raising Maneuver

TypeobservationalSponsorAnkara City Hospital BilkentRan2025 to 2026Enrolled50ConditionsFluid Responsiveness, Passive Leg Raising, Corrected Carotid Flow Time
NCT07488182 not yet recruitingnot on this mapstarted 2026, after this paper: background citation

The Value of Preoperative Carotid Doppler Ultrasonography Parameters in Predicting Post-Induction Hypotension in Patients Undergoing Elective Non-Cardiac Surgery

TypeobservationalSponsorNecmettin Erbakan UniversityRan2026 to 2027Enrolled110ConditionsPost Induction Hypotension, Postoperative Morbidity
3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 9 citations in OpenAlex.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Issac CheongDepartment of Critical Care Medicine, Sanatorio de Los Arcos, Juan B. Justo 909, CABA, Buenos Aires, Argentina. issac_cheong@hotmail.com.ORCID http://orcid.org/0000-0002-8231-1528
Victoria Otero CastroDepartment of Critical Care Medicine, Sanatorio de Los Arcos, Juan B. Justo 909, CABA, Buenos Aires, Argentina.
Fernando Ariel SosaArgentinian Critical Care Ultrasonography Association (ASARUC), Buenos Aires, Argentina.
Bárbara Tort OribeDepartment of Critical Care Medicine, Hospital Alemán, Buenos Aires, Argentina.
María Florencia FrüchtenichtDepartment of Critical Care Medicine, Sanatorio de Los Arcos, Juan B. Justo 909, CABA, Buenos Aires, Argentina.
Francisco Marcelo TamagnoneArgentinian Critical Care Ultrasonography Association (ASARUC), Buenos Aires, Argentina.
Pablo Martín MerloArgentinian Critical Care Ultrasonography Association (ASARUC), Buenos Aires, Argentina.
Helios Salud · ARHospital Alemán · ARCentro Científico Tecnológico - San Juan · AR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeThe passive leg raising test (PLR) is a noninvasive method widely adopted to assess fluid responsiveness. We propose to explore if changes in the carotid flow assessed by echo-Doppler can predict fluid responsiveness after a PLR.

methodsWe conducted a performance diagnostic study in two intensive care units from Argentina between February and April 2022. We included patients with signs of tissular hypoperfusion that required fluid resuscitation. We labeled the patients as fluid responders when we measured, after a fluid bolus, an increase greater than 15% in the left ventricle outflow tract (LVOT) VTI in an apical 5-chamber view and we compared those results with the carotid flow (CF) velocity-time integral (VTI) from the left supraclavicular region in a semi-recumbent position and during the PLR.

resultsOf the 62 eligible patients, 50 patients (80.6%) were included. The area under the ROC curve for a change in CF VTI during the PLR test was 0.869 (95% CI 0.743-0.947). An increase of at least of 11% in the CF VTI with the PLR predicted fluid-responsiveness with a sensitivity of 77.3% (95% CI 54.6-92.2%) and specificity of 78.6% (95% CI 59-91.7%). The positive predictive value was 73.9% (95% CI 57.4-85.6%) and the negative predictive value was 81.5% (95% CI 66.5-90.7%). The positive likelihood ratio was 3.61 and the negative likelihood ratio was 0.29.

conclusionAn increase greater than 11% in CF VTI after a PLR may be useful to predict fluid responsiveness among critically ill patients.

Indexed as

Intensive Care UnitsLegHumansROC CurveCarotid flowFluid responsivenessHemodynamic monitoringPassive leg raisingPLRPOCUS

Identifiers

PMID37668901
PMCPMC10909041
OpenAlexW4386438113

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.