Evidence map›Paper›PMID 37668738›Full record

Trial reportSupportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer2023

Feasibility and safety of exercise during chemotherapy in people with gastrointestinal cancers: a pilot study.

Song Ee Park, Du Hwan Kim, Don-Kyu Kim, Joo Young Ha, Joung-Soon Jang, Jin Hwa Choi, In Gyu Hwang

Open access · hybridAbstract readClinical Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.4field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 8 citations in OpenAlex.

  1. Trial
  2. Review
  3. Article
  4. Article
  5. Review
  6. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 1 country.

Song Ee Park *Department of Internal Medicine, Chung-Ang University Gwang-Myeong Hospital, Chung-Ang University College of Medicine, Seoul, Korea.ORCID http://orcid.org/0000-0002-5890-5422
Du Hwan Kim *Chung-Ang University Integrated Oncology and Palliative Care Research Institute, Seoul, Korea.ORCID http://orcid.org/0000-0002-9980-8549
Don-Kyu KimDepartment of Rehabilitation Medicine, Chung-Ang University Gwang-Myeong Hospital, Chung-Ang University College of Medicine, Seoul, Korea.ORCID http://orcid.org/0000-0001-8619-830X
Joo Young HaDepartment of Internal Medicine, Veterans Health Service Medical Center, Seoul, Korea.ORCID http://orcid.org/0000-0002-4860-4458
Joung-Soon JangDepartment of Internal Medicine, Uijeongbu Eulji Medical Center, Eulji University, Uijeongbu Gyuonggido, Korea.ORCID http://orcid.org/0000-0003-3057-6388
Jin Hwa ChoiChung-Ang University Integrated Oncology and Palliative Care Research Institute, Seoul, Korea. bonnybee@cau.ac.kr.ORCID http://orcid.org/0000-0002-5568-7984
In Gyu HwangChung-Ang University Integrated Oncology and Palliative Care Research Institute, Seoul, Korea. oncology@cau.ac.kr.ORCID http://orcid.org/0000-0002-4250-4165
Chung-Ang University Hospital · KRChung-Ang University · KREulji University · KRVeterans Health Service Medical Center · KR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeSarcopenia is a poor prognostic factor in cancer patients, and exercise is one of the treatments to improve sarcopenia. However, there is currently insufficient evidence on whether exercise can improve sarcopenia in patients with advanced cancers. This study examined the feasibility of exercise in advanced gastrointestinal (GI) cancer patients treated with palliative chemotherapy.

methodsBetween 2020 and 2021, 30 patients were enrolled in a resistance and aerobic exercise program for six weeks. The exercise intervention program (EIP) consisted of low, moderate, and high intensity levels. Patients were asked to select the intensity level according to their ability. The primary endpoint was the feasibility of the EIP measured by compliance during the six weeks. A compliance of over 50% was considered acceptable. The secondary endpoints were changes in weight and muscle mass, safety, quality of life (QoL) and overall survival (OS).

resultsThe median age of the study's participants was 60 (30-77). The total compliance to the EIP was 63.3% (19/30 patients). Sixteen (53.3%) patients had a compliance of over 80%. The attrition rate was 30.0% (9/30). The mean exercise time was 41.4 min, and the aerobic exercise was 92.3% and the resistant exercise was 73.7%, and both exercise was 66.5%. Most patients performed the moderate intensity level exercises at home or near their home. The mean skeletal muscle index (SMI) was 43.5 cm

conclusionsThe EIP during palliative chemotherapy in advanced GI cancer patients showed good compliance. In the good compliance group, muscle mass and physical functions were maintained for six weeks. The EIP was safe, and the QoL was maintained. Based on this study, further research in exercise intervention in advanced cancer patients is needed. CLINICAL

trial registrationThe clinical trial registration number is KCT 0005615 (CRIS, https://cris.nih.go.kr/cris/en/ ); registration date, 23rd Nov 2020.

Indexed as

ExerciseGastrointestinal NeoplasmsAdultAgedFeasibility StudiesHumansMiddle AgedPilot ProjectsQuality of LifeSarcopeniaCancerChemotherapyExerciseOverall survival

Identifiers

PMID37668738
PMCPMC10480261
OpenAlexW4386439136

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.