Zinc excess impairs

Xiaohui Li, Liu Chen, Yuankun Wang, Xiao Guo, Zheng-Guo He

Open access · goldAbstract read

In one paragraph

Article in Microbiology spectrum, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it

0cells of the map it votes in

1citing papers in PubMed

0.5field-weighted citation impact, top 38% of its field

1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 3 citations in OpenAlex.

AACS infectious diseases · 2025
Article

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Xiaohui LiState Key Laboratory for Conservation and Utilization of Subtropical Agro-bioresources, Guangxi Research Center for Microbial and Enzyme Engineering Technology, College of Life Science and Technology, Guangxi University , Nanning, Guangxi, China.ORCID 0000-0001-7009-4776

Liu ChenCollege of Life Science and Technology, Huazhong Agricultural University , Wuhan, Hubei, China.

Yuankun WangState Key Laboratory for Conservation and Utilization of Subtropical Agro-bioresources, Guangxi Research Center for Microbial and Enzyme Engineering Technology, College of Life Science and Technology, Guangxi University , Nanning, Guangxi, China.

Xiao GuoState Key Laboratory for Conservation and Utilization of Subtropical Agro-bioresources, Guangxi Research Center for Microbial and Enzyme Engineering Technology, College of Life Science and Technology, Guangxi University , Nanning, Guangxi, China.

Zheng-Guo HeState Key Laboratory for Conservation and Utilization of Subtropical Agro-bioresources, Guangxi Research Center for Microbial and Enzyme Engineering Technology, College of Life Science and Technology, Guangxi University , Nanning, Guangxi, China.ORCID 0000-0001-8621-7232

Guangxi University · CNHuazhong Agricultural University · CN

Funding

Ba-Gui Scholar Program of GuangxiChina Postdoctoral Science Foundation 2021M690764MOST | National Key Research and Development Program of China (NKPs) 2020YFA0907200MOST | National Natural Science Foundation of China (NSFC) 31730005

6 · The paper itself

Abstract

importanceAs a catalytic and structural cofactor of proteins, zinc is essential for almost all living organisms. However, zinc excess is toxic and represents a vital innate immunity strategy of macrophages to combat intracellular pathogens, especially against mycobacterial pathogens such as

Indexed as

iron homeostasismycobacterial survivalMycobacterium bovistranscription regulatorzinc toxicity

Identifiers

PMID37668384

DOI10.1128/spectrum.01069-23

PMCPMC10580935

OpenAlexW4386438054

What OpenQuestion holds

Textmetadata

LicenceCC BY

Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.