Evidence map›Paper›PMID 37668369›Full record

ArticleJournal of virology2023

Evolutionary conservation of an ancient retroviral

J'Zaria Simpson, Christine A Kozak, Guney Boso

Open access · greenAbstract read
In one paragraph

Article in Journal of virology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.8field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 2 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

J'Zaria SimpsonLaboratory of Molecular Microbiology, National Institute of Allergy and Infectious Diseases , Bethesda, Maryland, USA.
Christine A KozakLaboratory of Molecular Microbiology, National Institute of Allergy and Infectious Diseases , Bethesda, Maryland, USA.ORCID 0000-0001-5863-6915
Guney BosoLaboratory of Molecular Microbiology, National Institute of Allergy and Infectious Diseases , Bethesda, Maryland, USA.ORCID 0000-0002-1326-2953
National Institute of Allergy and Infectious Diseases · US

Funding

GENETIC CONTROL OF RESISTANCE TO FRIEND VIRUS IN WILD MOUSE POPULATIONSZ01AI000300 · NIAID · NIAID EXTRAMURAL ACTIVITIES · PI KOZAK, CHRISTINE · 1985 to 2008
$1.3M
Intramural NIH HHS Z01 AI000300
6 · The paper itself

Abstract

The genomes of mammals contain fingerprints of past infections by ancient retroviruses that invaded the germline of their ancestors. Most of these endogenous retroviruses (ERVs) contain only remnants of the original retrovirus; however, on rare occasions, ERV genes can be co-opted for a beneficial host function. While most studies of co-opted ERVs have focused on envelope genes, including the syncytins that function in placentation, there are examples of co-opted

Indexed as

ArtiodactylaEndogenous RetrovirusesAnimalsCamelusEvolution, MolecularPhylogenyRibonuclease HRNA-Directed DNA PolymeraseSwineRibonuclease HRNA-Directed DNA Polymerasecamel ERVsco-opted retroviral gagpol genedomesticated gag genesdomesticated pol genesendogenous retrovirusesendogenous retroviruses of even-toed ungulatesreverse transcriptase of ERVs

Identifiers

PMID37668369
PMCPMC10537755
OpenAlexW4386437781

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.