Evidence map›Paper›PMID 37668079›Full record

ReviewJournal of gynecologic oncology2023

RAIDS atlas of significant genetic and protein biomarkers in cervical cancer.

Suzy Scholl, Diana Bello Roufai, Linda Larbi Chérif, Maud Kamal

Open access · diamondAbstract readReview
In one paragraph

Review in Journal of gynecologic oncology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.8field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 3 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Suzy SchollDepartment of Drug Development and Innovation (D3i), Institut Curie, Paris, France.ORCID 0000-0003-0277-6219
Diana Bello RoufaiDepartment of Medical Oncology, Institut Curie, Saint-Cloud, France.ORCID 0000-0002-2817-7866
Linda Larbi ChérifDepartment of Drug Development and Innovation (D3i), Institut Curie, Paris, France.
Maud KamalDepartment of Drug Development and Innovation (D3i), Institut Curie, Paris, France.ORCID 0000-0003-1466-0950
Institut Curie · FR

Funding

Ames Research Center NASA 304,810
6 · The paper itself

Abstract

Loss of function in epigenetic acting genes together with driver alterations in the PIK3CA pathway have been shown significantly associated with poor outcome in cervical squamous cell cancer. More recently, a CoxBoost analysis identified 16 gene alterations and 30 high level activated proteins to be of high interest, due to their association with either good or bad outcome, in the context of treatment received by chemoradiation. The objectives here were to review and confirm the significance of these molecular alterations as suggested by literature reports and to pinpoint alternate treatments options for poor-responders to chemoradiation.

Indexed as

Carcinoma, Squamous CellUterine Cervical NeoplasmsBiomarkersChemoradiotherapyFemaleHumansBiomarkersBioRAIDsChemoradiationGenetic & Proteomic BiomarkersPost Translational Protein ModificationsTargeted TreatmentsTreatment Combinations

Identifiers

PMID37668079
PMCPMC10482580
OpenAlexW4386106677

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.