Evidence map›Paper›PMID 37668046›Full record

ArticleTurkish journal of obstetrics and gynecology2023

Clinical and genetic aspects of termination of pregnancy; tertiary center experience.

Ömer Gökhan Eyisoy, Çağdaş Özgökçe, Lütfiye Uygur, Mucize Eriç Özdemir, Ümit Taşdemir, Aydın Öcal, Oya Demirci

Abstract read
In one paragraph

Article in Turkish journal of obstetrics and gynecology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Ömer Gökhan EyisoyUniversity of Health Sciences Turkey, Zeynep Kamil Women and Children Diseases Training and Research Hospital, Clinic of Perinatology, İstanbul, Turkey.ORCID 0000-0003-0869-4660
Çağdaş ÖzgökçeUniversity of Health Sciences Turkey, Zeynep Kamil Women and Children Diseases Training and Research Hospital, Clinic of Perinatology, İstanbul, Turkey.ORCID 0000-0003-4960-4625
Lütfiye UygurUniversity of Health Sciences Turkey, Zeynep Kamil Women and Children Diseases Training and Research Hospital, Clinic of Perinatology, İstanbul, Turkey.ORCID 0000-0002-6325-1910
Mucize Eriç ÖzdemirUniversity of Health Sciences Turkey, Zeynep Kamil Women and Children Diseases Training and Research Hospital, Clinic of Perinatology, İstanbul, Turkey.ORCID 0000-0002-2177-0771
Ümit TaşdemirUniversity of Health Sciences Turkey, Zeynep Kamil Women and Children Diseases Training and Research Hospital, Clinic of Perinatology, İstanbul, Turkey.ORCID 0000-0001-9745-6327
Aydın ÖcalUniversity of Health Sciences Turkey, İstanbul Haseki Training and Reseasch Hospital, Clinic of Obstetrics, Division of Perinatology, İstanbul, Turkey.ORCID 0000-0002-6027-1094
Oya DemirciUniversity of Health Sciences Turkey, Zeynep Kamil Women and Children Diseases Training and Research Hospital, Clinic of Perinatology, İstanbul, Turkey.ORCID 0000-0001-5578-4437

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objective: The aim of the study was to retrospectively analyze the indications Techniques and complications of pregnancy termination performed in a tertiary center. Materials and Methods: All cases between 10 and 33 weeks of gestation between January 2021 and June 2023 were retrospectively analyzed. The patients were divided into two groups as group 1 with 11+0 to 21+6 gestational weeks and group 2 for those at 22+0 and 33+0 gestational weeks. Results: A total of 568 pregnancy terminations were included in the study. Among all terminations the most common fetal indications were central nervous system anomalies (148 cases, 26%) and trisomy 21 (53 cases, 9%) and the most common maternal/obstetrical Indication was previable premature rupture of the membranes (179 cases, 31.5%). Abnormal genetic results were found in 50 of 173 cases (28.9%) with a termination indication of Structural malformation who accepted invaziv genetic testing. The number of terminations with fetal indications performed after 22 weeks were 148 (41%) and 11 (7.4%) cases of these late terminations of pregnancy were anomalies expected to be diagnosed in the first trimester. Complication rates (12.4%) and abdominal termination rates (3.5%) were significantly higher in group 2 than in group 1 (p<0.05). Conclusion: Improvements in prenatal genetic screening and diagnostic techniques will undoubtedly decrease the gestational ages in terminations of pregnancies. However, there will always be cases that can neither be diagnosed earlier nor can be treated due to the nature of the anomaly. In the management of such cases, terminations will always occupy an important place in prenatal care.

Indexed as

congenital anomalyFetal ultrasonographypregnancy complicationsprenatal diagnosis

Identifiers

PMID37668046
PMCPMC10478725

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.