Evidence map›Paper›PMID 37667992›Full record

ReviewJournal of cachexia, sarcopenia and muscle2023

Diagnosis and outcomes of cachexia in Asia: Working Consensus Report from the Asian Working Group for Cachexia.

Hidenori Arai, Keisuke Maeda, Hidetaka Wakabayashi, Tateaki Naito, Masaaki Konishi, Prasert Assantachai, Wai Tung Auyeung, Chalobol Chalermsri, Wei Chen, Justin Chew and 29 more

Open access · goldAbstract readConsensus StatementReview
In one paragraph

Review in Journal of cachexia, sarcopenia and muscle, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 55 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
55citing papers in PubMed, 1 pooled it
17.5field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

55 citing papers in PubMed, 1 synthesis or guideline pooled it, 100 citations in OpenAlex.

  1. Pooled it
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  3. Review
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  7. Observational
  8. Article
  9. Article
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  12. Weight change and impact on prognosis in patients with advanced non-small cell lung cancer with concomitant diabetes mellitus treated with sglt2 inhibitors.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2026
    Article
  13. Article
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  17. Cancer cachexia: molecular basis and therapeutic advances.Signal transduction and targeted therapy · 2026
    Review
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  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

39 authors at 20 institutions in 10 countries.

Hidenori AraiNational Center for Geriatrics and Gerontology, Obu, Japan.ORCID 0000-0001-6747-8680
Keisuke MaedaNutrition Therapy Support Center, Aichi Medical University Hospital, Nagakute, Japan.ORCID 0000-0001-7132-7818
Hidetaka WakabayashiDepartment of Rehabilitation Medicine, Tokyo Women's Medical University Hospital, Tokyo, Japan.
Tateaki NaitoDivision of Thoracic Oncology, Shizuoka Cancer Center, Shizuoka, Japan.
Masaaki KonishiDepartment of Cardiology, Yokohama City University School of Medicine, Yokohama, Japan.
Prasert AssantachaiFaculty of Medicine Siriraj Hospital, Mahidol University, Bangkok, Thailand.
Wai Tung AuyeungJockey Club Institute of Ageing, The Chinese University of Hong Kong, Shatin, Hong Kong, China.
Chalobol ChalermsriDepartment of Preventive and Social Medicine, Division of Geriatric Medicine, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok, Thailand.
Wei ChenDepartment of Clinical Nutrition, Department of Health Medicine, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China.
Justin ChewDepartment of Geriatric Medicine, Tan Tock Seng Hospital, Singapore.
Ming-Yueh ChouCenter for Geriatrics and Gerontology, Kaohsiung Veterans General Hospital, Kaohsiung City, Taiwan.
Chih-Cheng HsuNational Center for Geriatrics and Welfare Research, Miaoli County, Taiwan.
Allyn HumDepartment of Geriatrics and Palliative Care, Tan Tock Seng Hospital, Singapore.
In Gyu HwangDepartment of Internal Medicine, Chung-Ang University Hospital, Chung-Ang University College of Medicine, Seoul, Republic of Korea.
Toshimi KaidoDepartment of Gastroenterological and General Surgery, St. Luke's International Hospital, Tokyo, Japan.
Lin KangDepartment of Geriatric Medicine, Peking Union Medical College Hospital, Beijing, China.
Shahrul Bahyah KamaruzzamanDepartment of Medicine, Faculty of Medicine, Universiti Malaya, Kuala Lumpur, Malaysia.
Miji KimDepartment of Biomedical Science and Technology, College of Medicine, East-West Medical Research Institute, Kyung Hee University, Seoul, Republic of Korea.
Jenny Shun Wah LeeInstitute of Aging, The Chinese University of Hong Kong, Department of Medicine, Alice Ho Miu Ling Nethersole Hospital, Tai Po, Hong Kong.
Wei-Ju LeeAging and Health Research Center, National Yang Ming Chiao Tung University, Taipei City, Taiwan.
Chih-Kuang LiangCenter for Geriatrics and Gerontology, Kaohsiung Veterans General Hospital, Kaohsiung City, Taiwan.
Wee Shiong LimDepartment of Geriatric Medicine, Institute of Geriatric Medicine, Tan Tock Seng Hospital, Singapore.
Jae-Young LimDepartment of Rehabilitation Medicine, Seoul National University College of Medicine, Seoul National University Bundang Hospital, Seongnam, Republic of Korea.
Yen Peng LimDepartment of Nutrition and Dietetics, Tan Tock Seng Hospital, Singapore.
Raymond See-Kit LoDepartment of Medicine and Therapeutics, Chinese University of Hong Kong, Shatin Hospital, Ma On Shan, Hong Kong.
Terence OngDepartment of Medicine, Faculty of Medicine, University Malaya, Kuala Lumpur, Malaysia.
Wen-Harn PanInstitute of Biomedical Sciences, Academia Sinica, Taiwan, Taipei City, Taiwan.
Li-Ning PengAging and Health Research Center, National Yang Ming Chiao Tung University, Taipei City, Taiwan.
Pornpoj PramyothinDivision of Nutrition, Department of Medicine, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok, Thailand.
Nurul Huda RazalliCentre for Healthy Aging and Wellness (H-CARE), Faculty of Health Sciences, Universiti Kebangsaan Malaysia, Universiti Kebangsaan Malaysia, Jalan Raja Muda Abdul Aziz, Kuala Lumpur, Malaysia.
Masakazu SaitohDepartment of Physical Therapy, Faculty of Health Science, Juntendo University, Tokyo, Japan.
Suzana ShaharCenter for Healthy Aging and Wellness, Faculty Health Sciences, Universiti Kebangsaan Malaysia, Kuala Lumpur, Malaysia.
Han Ping ShiDepartment of Gastrointestinal Surgery, Department of Clinical Nutrition, Beijing Shijitan Hospital, Capital Medical University of China, Beijing, China.
Heng-Hsin TungNational Yang Ming Chiao Tung University, Taipei City, Taiwan.
Yasuhito UezonoDepartment of Pain Control Research, The Jikei University School of Medicine, Tokyo, Japan.
Stephan von HaehlingDepartment of Cardiology and Pneumology, University of Goettingen Medical Center, Georg-August-University Goettingen, Goettingen, Germany.
Chang Won WonDepartment of Family Medicine, College of Medicine, Kyung Hee University, Seoul, Republic of Korea.
Jean WooDepartment of Medicine & Therapeutics, The Chinese University of Hong Kong, Prince of Wales Hospital, Hong Kong SAR, China.
Liang-Kung ChenCenter for Healthy Longevity and Aging Sciences, National Yang Ming Chiao Tung University, Taipei City, Taiwan.
National Yang Ming Chiao Tung University · TWChinese University of Hong Kong · HKTan Tock Seng Hospital · SGChinese Academy of Medical Sciences & Peking Union Medical College · CNKyung Hee University · KRNational University of Malaysia · MYSiriraj Hospital · THUniversity of Malaya · MYAichi Medical University Hospital · JPCapital Medical University · CNChung-Ang University Hospital · KRGerman Centre for Cardiovascular Research · DEInstitute of Biomedical Sciences, Academia Sinica · TWJikei University School of Medicine · JPJuntendo University · JPKaohsiung Veterans General Hospital · TWNanyang Technological University · SGNational Center for Geriatrics and Gerontology · JPNational United University · TWSeoul National University Bundang Hospital · KR

Funding

Japan Society for the Promotion of Science 21H03390Japan Society for the Promotion of Science 22K11346Research Funding of Longevity Sciences 22-4
6 · The paper itself

Abstract

Chronic diseases often lead to metabolic disorders, causing anabolic resistance and increased energy consumption, which result in cachexia. Cachexia, in turn, can lead to major clinical consequences such as impaired quality of life, shortened life expectancy, and increased healthcare expenditure. Existing international diagnostic criteria for cachexia employ thresholds derived from Western populations, which may not apply to Asians due to differing body compositions. To address this issue, the Asian Working Group for Cachexia (AWGC) was initiated. The AWGC comprises experts in cachexia research and clinical practice from various Asian countries and aims to develop a consensus on diagnostic criteria and significant clinical outcomes for cachexia in Asia. The AWGC, composed of experts in cachexia research and clinical practice from several Asian countries, undertook three-round Delphi surveys and five meetings to reach a consensus. Discussions were held on etiological diseases, essential diagnostic items for cachexia, including subjective and objective symptoms and biomarkers, and significant clinical outcomes. The consensus highlighted the importance of multiple diagnostic factors for cachexia, including chronic diseases, either or both weight loss or low body mass index, and at least one of the following: anorexia, decreased grip strength (<28 kg in men and <18 kg in women), or elevated C-reactive protein levels (>5 mg/L [0.5 mg/dL]). The AWGC proposed a significant weight change of 2% or more over a 3-6 month period and suggested a tentative cut-off value of 21 kg/m

Indexed as

CachexiaAsiaHumansQuality of LifeAsianCachexiaDiagnostic criteriaEthnicityExpert opinionPosition paper

Identifiers

PMID37667992
PMCPMC10570088
OpenAlexW4386438593

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.