Evidence map›Paper›PMID 37667488›Full record

ArticlePharmaceutical biology2023

Saponins from

Cheng Fan, Jin-Xin Wang, Zhang-E Xiong, Shan-Shan Hu, Ao-Jia Zhou, Ding Yuan, Chang-Cheng Zhang, Zhi-Yong Zhou, Ting Wang

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Pharmaceutical biology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.1field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 6 citations in OpenAlex.

  1. Review
  2. Review
  3. Review
  4. Review
  5. Induction and Suspension Culture ofPlants (Basel, Switzerland) · 2024
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 1 country.

Cheng FanInstitute of Pharmaceutical Process, Academy of Nutrition and Health Hubei Province Key Laboratory of Occupational Hazard Identification and Control School of Medicine, Wuhan University of Science and Technology Wuhan, China.
Jin-Xin WangCollege of Medical Science, Three Gorges University, Yichang, Hubei, China.
Zhang-E XiongDepartment of Gastroenterology, Wuhan Third Hospital, Wuhan, China.
Shan-Shan HuCollege of Medical Science, Three Gorges University, Yichang, Hubei, China.
Ao-Jia ZhouInstitute of Pharmaceutical Process, Academy of Nutrition and Health Hubei Province Key Laboratory of Occupational Hazard Identification and Control School of Medicine, Wuhan University of Science and Technology Wuhan, China.
Ding YuanCollege of Medical Science, Three Gorges University, Yichang, Hubei, China.
Chang-Cheng ZhangCollege of Medical Science, Three Gorges University, Yichang, Hubei, China.
Zhi-Yong ZhouCollege of Medical Science, Three Gorges University, Yichang, Hubei, China.
Ting WangInstitute of Pharmaceutical Process, Academy of Nutrition and Health Hubei Province Key Laboratory of Occupational Hazard Identification and Control School of Medicine, Wuhan University of Science and Technology Wuhan, China.ORCID 0000-0002-5925-0237
China Three Gorges University · CNWuhan University of Science and Technology · CNWuhan Third Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

context

objectiveWe evaluated the neuroprotective effects of SPJ on aging rats. MATERIALS AND

methodsSprague-Dawley rats (18-months-old) were randomly divided into aging and SPJ groups (

resultsSPJ improved the neuronal degeneration and mitochondrial morphology that are associated with aging. Meanwhile, SPJ up-regulated the protein levels of mitofusin 2 (Mfn2) and optic atrophy 1 (Opa1) and down-regulated the protein level of dynamin-like protein 1 (Drp1) in the hippocampus of aging rats ( DISCUSSION AND

conclusionsFurther research on the elderly population will contribute to the development and utilization of SPJ for the treatment of neurodegenerative disorders.

Indexed as

NeuroblastomaPanaxAgedAgingAnimalsGalactoseHumansMitochondriaRatsRats, Sprague-DawleyGalactosemitochondrial fission fusionmitochondrial functionSPJ

Identifiers

PMID37667488
PMCPMC10484050
OpenAlexW4386438695

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.