Evidence map›Paper›PMID 37667389›Full record

ArticleJournal of nanobiotechnology2023

Selenium-integrated conjugated oligomer nanoparticles with high photothermal conversion efficiency for NIR-II imaging-guided cancer phototheranostics in vivo.

Lele Yang, Yijian Gao, Jinchao Wei, Zehua Cheng, Sijia Wu, Liang Zou, Shengliang Li, Peng Li

Abstract read
In one paragraph

Article in Journal of nanobiotechnology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Lele Yang *State Key Laboratory of Quality Research in Chinese Medicine, Institute of Chinese Medical Sciences, University of Macau, Macau, 999078, China.
Yijian Gao *College of Pharmaceutical Sciences, Soochow University, Suzhou, 215000, China.
Jinchao Wei *State Key Laboratory of Quality Research in Chinese Medicine, Institute of Chinese Medical Sciences, University of Macau, Macau, 999078, China.
Zehua ChengState Key Laboratory of Quality Research in Chinese Medicine, Institute of Chinese Medical Sciences, University of Macau, Macau, 999078, China.
Sijia WuState Key Laboratory of Quality Research in Chinese Medicine, Institute of Chinese Medical Sciences, University of Macau, Macau, 999078, China.
Liang ZouSchool of Medicine, Chengdu University, Chengdu, 610106, China.
Shengliang LiCollege of Pharmaceutical Sciences, Soochow University, Suzhou, 215000, China. lishengliang@suda.edu.cn.
Peng LiState Key Laboratory of Quality Research in Chinese Medicine, Institute of Chinese Medical Sciences, University of Macau, Macau, 999078, China. pli1978@hotmail.com.

Funding

Jiangsu Specially Appointed Professorship, Leading Talents of Innovation and Entrepreneurship of Gusu ZXL2022496Macau Science and Technology Development Fund 0014/2022/ITPMacau Science and Technology Development Fund 0024/2021/A1National Natural Science Foundation of China 52173135National Natural Science Foundation of China 81903794Research Committee of the University of Macau MYRG2022-00226-ICMSResearch Committee of the University of Macau SRG2022-00035-ICMSScience and Technology Program of Suzhou SKY2022039
6 · The paper itself

Abstract

Second near-infrared (NIR-II) fluorescence imaging in the range of 1000-1700 nm has great prospects for in vivo imaging and theranostics monitoring. At present, few NIR-II probes with theranostics properties have been developed, especially the high-performance organic theranostics material remains underexploited. Herein, we demonstrate a selenium (Se)-tailoring method to develop high-efficient NIR-II imaging-guided material for in vivo cancer phototheranostics. Via Se-tailoring strategy, conjugated oligomer TPSe-based nanoparticles (TPSe NPs) achieve bright NIR-II emission up to 1400 nm and exhibit a relatively high photothermal conversion efficiency of 60% with good stability. Moreover, the TPSe NPs demonstrate their photothermal ablation of cancer cells in vitro and tumor in vivo with the guidance of NIR-II imaging. It is worth noting that the TPSe NPs have good biocompatibility without obvious side effects. Thus, this work provides new insight into the development of NIR-II theranostics agents.

Indexed as

NanoparticlesNeoplasmsSeleniumHumansOptical ImagingSeleniumCancerFluorescence imagingNanoparticlesNIR II-responsePhotothermal therapy

Identifiers

PMID37667389
PMCPMC10476403

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.