Evidence map›Paper›PMID 37667095›Full record

ArticleBiological trace element research2024

Effect of Zinc Oxide Nanoparticles as Feed Additive on Blood Indices, Physiological, Immunological Responses, and Histological Changes in Broiler Chicks.

Mahmoud H Hatab, Aml M M Badran, Mahmoud A Elaroussi, Eman Rashad, Adel M Abu Taleb, Abdelmotaleb A Elokil

Open access · hybridAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Biological trace element research, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed, 1 pooled it
2.4field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 1 synthesis or guideline pooled it, 13 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Review
  4. Article
  5. Article
  6. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 4 institutions in 1 country.

Mahmoud H HatabBiological Application Department, Nuclear Research Center, Egyptian Atomic Energy Authority, P.O. Box 13759, Cairo, Egypt. hatabmahmoud@yahoo.com.
Aml M M BadranPoultry Breeding Department, Animal Production Research Institute, Agriculture Research Center, Ministry of Agriculture, Dokki, Giza, Egypt.
Mahmoud A ElaroussiBiological Application Department, Nuclear Research Center, Egyptian Atomic Energy Authority, P.O. Box 13759, Cairo, Egypt.
Eman RashadCytology and Histology Department, Faculty of Veterinary Medicine, Cairo University, Giza, Egypt.
Adel M Abu TalebBiological Application Department, Nuclear Research Center, Egyptian Atomic Energy Authority, P.O. Box 13759, Cairo, Egypt.
Abdelmotaleb A ElokilAnimal Production Department, Faculty of Agriculture, Benha University, Moshtohor, Egypt.
Egyptian Atomic Energy Authority · EGBenha University · EGCairo University · EGMinistry of Agriculture and Land Reclamation · EG

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A feeding trial of 5-week duration was performed to assess the response of broiler chicks to dietary supplementation with different doses of myco-fabricated zinc oxide nanoparticles (ZONPs) on blood indices, physiological, immunological response, antioxidant status, intestinal microbial count, and histological changes in immune organs. A total of 162 3-day-old Ross 308 broiler chicks were weighed individually and distributed equally into 3 dietary treatments with 6 replicate of 9 chicks in each in a completely randomized design. Chicks were fed ad libitum a basal ration prepared as starter, grower, and finisher supplemented with 0 (T1, control), 40 (T2), and 60 (T3) mg zinc oxide nanoparticles (ZONPs)/kg feed. Results showed that supplementing with ZONPs at both studied levels increased the relative weights of the spleen, bursa, thymus, and liver and decreased the relative weight of the kidney, gizzard, and intestine. A significant increase in the concentrations of hemoglobin (Hb), hematocrit (PCV%), red and white blood cell counts, total protein (TP), globulin (GLOB), aspartate transferase (AST), alanine transferase (ALT), alkaline phosphatase (ALP), superoxide dismutase (SOD), glutathione peroxidase (GPx), and total antioxidant capacity (TAC) and a significant decrease in malonaldehyde (MDA), uric acid, and creatinine concentration were observed. Furthermore, all immunological organs showed histological alteration and increased both types of immunity in ZONPs groups with more pronounced effects in the T2 group.

Indexed as

NanoparticlesZinc OxideAnimal FeedAnimalsAntioxidantsChickensDietDietary SupplementsTransferasesAntioxidantsTransferasesZinc OxideAntioxidantsBlood indicesBroilersImmune responseZinc oxide nanoparticles

Identifiers

PMID37667095
PMCPMC10955013
OpenAlexW4386408488

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.