ArticleNature neuroscience2023
Dissociating the contributions of sensorimotor striatum to automatic and visually guided motor sequences.
Article in Nature neuroscience, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers.
What it found
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Who cites it
27 citing papers in PubMed.
- Abstract Representation of Movement Parameters in Basal Ganglia Output.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026Article
- The Tower Foraging Park: A paradigm for studying cognitive and motor processes underlying behavioral flexibility in freely moving mice.iScience · 2026Article
- Article
- Using deep learning to identify brain networks mediating cognitive and motor impairments in alcohol use disorder.Translational psychiatry · 2026Article
- Integration of Memory and Sensory Information in Skilled Sequence Production.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2026Article
- Neural representation of action symbols in primate frontal cortex.bioRxiv : the preprint server for biology · 2025Article
- Neural Associative Skill Memories for Safer Robotics and Modeling Human Sensorimotor Repertoires.Neural computation · 2025Article
- Neurodegenerative Disease Movement Disorders and Dorsal Striatum-Mediated Imbalance of Habitual Motor Sequences.Molecular neurobiology · 2025Review
- Encoding of motor sequences in primate globus pallidus and motor cortex: Uniform preference for ordinal position.bioRxiv : the preprint server for biology · 2025Article
- Differential kinematic coding in sensorimotor striatum across behavioral domains reflects different contributions to movement.Nature neuroscience · 2025Article
- A neural manifold view of the brain.Nature neuroscience · 2025Review
- Striatal pathways oppositely shift cortical activity along the decision axis.bioRxiv : the preprint server for biology · 2025Article
- Dissociable Causal Roles of Dorsolateral Prefrontal Cortex and Primary Motor Cortex over the Course of Motor Skill Development.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2025Article
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- Article
- The role of motor cortex in motor sequence execution depends on demands for flexibility.Nature neuroscience · 2024Article
- Preconfigured cortico-thalamic neural dynamics constrain movement-associated thalamic activity.Nature communications · 2024Article
- Striatal Functional Hypoconnectivity in Patients With Schizophrenia Suffering From Negative Symptoms, Longitudinal Findings.Schizophrenia bulletin · 2024Article
- The Hippocampus Preorders Movements for Skilled Action Sequences.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2024Article
- Learning and Control in Motor Cortex across Cell Types and Scales.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2024Review
Corrections and comments
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Authors and funding
4 authors.
Funding
Abstract
The ability to sequence movements in response to new task demands enables rich and adaptive behavior. However, such flexibility is computationally costly and can result in halting performances. Practicing the same motor sequence repeatedly can render its execution precise, fast and effortless, that is, 'automatic'. The basal ganglia are thought to underlie both types of sequence execution, yet whether and how their contributions differ is unclear. We parse this in rats trained to perform the same motor sequence instructed by cues and in a self-initiated overtrained, or 'automatic,' condition. Neural recordings in the sensorimotor striatum revealed a kinematic code independent of the execution mode. Although lesions reduced the movement speed and affected detailed kinematics similarly, they disrupted high-level sequence structure for automatic, but not visually guided, behaviors. These results suggest that the basal ganglia are essential for 'automatic' motor skills that are defined in terms of continuous kinematics, but can be dispensable for discrete motor sequences guided by sensory cues.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.