Evidence map›Paper›PMID 37667016›Full record

Observational studyJournal of assisted reproduction and genetics2023

Embryo transfers performed during daylight savings time led to reduced live birth rates in older patients.

Ramon A Pelayo, Shuai Xu, Jessica R Walter

Open access · greenAbstract readObservational Study
In one paragraph

Observational study in Journal of assisted reproduction and genetics, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.8field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 3 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Ramon A PelayoNorthwestern University Feinberg School of Medicine, Chicago, IL, USA.
Shuai XuSibel Health, Chicago, IL, USA.
Jessica R WalterDivision of Reproductive Endocrinology and Infertility, Department of Obstetrics and Gynecology, Northwestern University Feinberg School of Medicine, 259 E Erie St Suite 2400, Chicago, IL, 60611, USA. Jessica.walter@northwestern.edu.ORCID http://orcid.org/0000-0002-8802-3391
Northwestern University · USSibel (United States) · US

Funding

Research Career Development in Obstetrics and GynecologyK12HD050121 · NICHD · NORTHWESTERN UNIVERSITY AT CHICAGO · PI Serdar E. Bulun · 2005 to 2026
$7.2M
NICHD NIH HHS K12 HD050121
6 · The paper itself

Abstract

purposeTo study the impact of undergoing an embryo transfer during the week of daylight savings time transition on live birth rates.

methodsWe performed a retrospective observational cohort study of patients undergoing embryo transfer at an academic infertility practice during the week of spring or fall daylight savings time transition (cases), or the 2 weeks preceding and following the daylight savings transition (controls) between 2015 and 2021. The primary exposure was completion of an embryo transfer during the week of daylight savings time transition. The primary outcome was a comparison of live birth rate per embryo transfer among individuals undergoing an embryo transfer during the week of daylight savings time (DST) transition and those who did not.

resultsA total of 309 embryo transfers occurred during the week of daylight savings transition and 1242 embryo transfers occurred in the control group outside of the daylight savings transition week. The live birth rate after embryo transfer during DST transition weeks was 39.2% (121/309) compared to 40.8% (507/1242) (p = 0.59). When restricting the analysis to individuals (age > 37 years), the live birth rate after embryo transfer during DST transition week was 23.5% (24/102) compared to 34.8% (149/429) (p = 0.03). This difference persisted in the mixed-effects regression model demonstrating that after adjusting for relevant covariates, embryo transfer during DST transition weeks resulted in a 45% decrease in the odds of achieving a live birth.

conclusionDaylight savings time transition may be associated with less favorable outcomes after embryo transfer among an older infertile patient population. Future work is needed to prospectively examine the influence of circadian rhythm disruption on reproductive outcomes.

Indexed as

Birth RateInfertilityAdultAgedEmbryo TransferFemaleFertilization in VitroHumansLive BirthPregnancyPregnancy RateRetrospective StudiesCircadian rhythmIVF outcomesSleep

Identifiers

PMID37667016
PMCPMC10643731
OpenAlexW4386425386

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.