Evidence map›Paper›PMID 37667012›Full record

ArticleNature chemistry2023

Precisely patterned nanofibres made from extendable protein multiplexes.

Neville P Bethel, Andrew J Borst, Fabio Parmeggiani, Matthew J Bick, T J Brunette, Hannah Nguyen, Alex Kang, Asim K Bera, Lauren Carter, Marcos C Miranda and 5 more

Open access · hybridAbstract read
In one paragraph

Article in Nature chemistry, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
6.9field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 28 citations in OpenAlex.

  1. Article
  2. Chemical reviews · 2026
    Review
  3. Review
  4. Stimuli-triggered formation ofCell biomaterials · 2026
    Article
  5. Designability of α-Helical Protein Filaments.Sub-cellular biochemistry · 2026
    Review
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Review
  12. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 4 institutions in 2 countries.

Neville P BethelDepartment of Biochemistry, University of Washington, Seattle, WA, USA.ORCID 0000-0001-7576-9613
Andrew J BorstDepartment of Biochemistry, University of Washington, Seattle, WA, USA.ORCID 0000-0003-4297-7824
Fabio ParmeggianiSchool of Chemistry, University of Bristol, Bristol, UK.ORCID 0000-0001-8548-1090
Matthew J BickDepartment of Biochemistry, University of Washington, Seattle, WA, USA.
T J BrunetteDepartment of Biochemistry, University of Washington, Seattle, WA, USA.
Hannah NguyenDepartment of Biochemistry, University of Washington, Seattle, WA, USA.
Alex KangDepartment of Biochemistry, University of Washington, Seattle, WA, USA.
Asim K BeraDepartment of Biochemistry, University of Washington, Seattle, WA, USA.ORCID 0000-0001-9473-2912
Lauren CarterDepartment of Biochemistry, University of Washington, Seattle, WA, USA.
Marcos C MirandaDepartment of Biochemistry, University of Washington, Seattle, WA, USA.ORCID 0000-0002-2839-6997
Ryan D KiblerDepartment of Biochemistry, University of Washington, Seattle, WA, USA.ORCID 0000-0001-6984-9887
Mila LambDepartment of Biochemistry, University of Washington, Seattle, WA, USA.
Xinting LiDepartment of Biochemistry, University of Washington, Seattle, WA, USA.
Banumathi SankaranBerkeley Center for Structural Biology, Molecular Biophysics and Integrated Bioimaging, Lawrence Berkeley Laboratory, Berkeley, CA, USA.ORCID 0000-0002-3266-8131
David BakerDepartment of Biochemistry, University of Washington, Seattle, WA, USA. dabaker@uw.edu.ORCID 0000-0001-7896-6217
University of Washington · USHoward Hughes Medical Institute · USAt Bristol · GBLawrence Berkeley National Laboratory · US

Funding

User Training and OutreachP30GM124165 · NIGMS · CORNELL UNIVERSITY · PI Nozomi Ando, J Christopher Fromme · 2018 to 2026
$34.2M
User Training and OutreachP30GM124169 · NIGMS · UNIVERSITY OF CALIF-LAWRENC BERKELEY LAB · PI PAUL David ADAMS, Gregory L Hura · 2017 to 2026
$28.6M
A Pixel Array Detector System for Small Angle X-ray ScatteringS10OD018483 · OD · UNIVERSITY OF CALIF-LAWRENC BERKELEY LAB · PI CLASSEN, SCOTT · 2014 to 2014
$998k
Biotechnology and Biological Sciences Research Council BB/L01386X/1NIGMS NIH HHS P30 GM124165NIGMS NIH HHS P30 GM124169NIH HHS S10 OD018483
6 · The paper itself

Abstract

Molecular systems with coincident cyclic and superhelical symmetry axes have considerable advantages for materials design as they can be readily lengthened or shortened by changing the length of the constituent monomers. Among proteins, alpha-helical coiled coils have such symmetric, extendable architectures, but are limited by the relatively fixed geometry and flexibility of the helical protomers. Here we describe a systematic approach to generating modular and rigid repeat protein oligomers with coincident C

Indexed as

NanofibersModels, MolecularProtein Conformation, alpha-HelicalProtein SubunitsProtein Subunits

Identifiers

PMID37667012
PMCPMC10695826
OpenAlexW4386423803

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.