ArticleScientific reports2023
Correlation of systolic and diastolic blood pressure with echocardiographic phenotypes of cardiac structure and function from three German population-based studies.
Article in Scientific reports, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.
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Who cites it
9 citing papers in PubMed, 9 citations in OpenAlex.
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- Impact of Radiation Therapy on Diastolic Function and Cardiac Troponin I Levels in Cancer Patients Undergoing Contemporary Radiotherapy.Circulation reports · 2026Article
- Association of Cardiovascular Health and Genetic Risk for Left Ventricular Mass with Left Ventricular Structure, Function, and Incident Cardiovascular Outcomes.medRxiv : the preprint server for health sciences · 2026Article
- Optimize speckle-tracking echocardiography screening in CKD patients: a TyG index-based nomogram model.Frontiers in cardiovascular medicine · 2026Article
- Integrating traditional Chinese pulse diagnosis with machine learning: novel approaches for pregnancy and coronary heart disease identification.Scientific reports · 2025Article
- Brain‑heart axis: Neurostimulation techniques in ischemic heart disease (Review).International journal of molecular medicine · 2025Review
- Subclinical systolic dysfunction in children with steroid-resistant nephrotic syndrome identified by speckle tracking echocardiography.BMC pediatrics · 2025Article
- Analysis of Energy and Pressure in the Sinus with Different Blood Pressures after Bioprosthetic Aortic Valve Replacement.Annals of biomedical engineering · 2024Article
- 24-h central pressure is a valuable predictor for left ventricular hypertrophy in non-dialysis patients with chronic kidney disease.Hypertension research : official journal of the Japanese Society of Hypertension · 2024Article
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13 authors at 6 institutions in 2 countries.
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Abstract
Arterial hypertension is considered a risk factor for the development of heart failure. Here we investigate cross-sectional associations of systolic and diastolic blood pressure with subtle functional and morphological changes of left ventricular echocardiographic parameters representing early dysfunction in three representative German population-based studies. We assessed 26,719 individuals without symptomatic heart failure from the Hamburg City Health Study (HCHS, n = 7396, derivation cohort), the Gutenberg Health Study (GHS, 14,715, validation cohort) and the Study of Health in Pomerania (SHIP, 4608, validation cohort). Multivariable linear regression analyses with systolic and diastolic blood pressure as continuous exposure variables were adjusted for common cardiovascular risk factors and antihypertensive medication. Both systolic and diastolic blood pressure were consistently associated with measures of left ventricular hypertrophy (β per standard deviation (SD) for LV mass (g) and systolic blood pressure: 5.09 (p < 0.001); diastolic blood pressure: 2.29 (p < 0.001) in HCHS). Systolic blood pressure correlated with declining diastolic function (β per SD for E/e': 0.29, p < 0.001 in HCHS) and diastolic blood pressure with declining systolic function (β per SD for LVEF, in %: - 0.15; p = 0.041 in HCHS) in all cohorts. Pending further validation, our results from three independent German population samples suggest differential effects of systolic versus diastolic blood pressure on left ventricular structure and function.
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