Evidence map›Paper›PMID 37666925›Full record

ArticleScientific reports2023

Assessment of exercise-induced stress via automated measurement of salivary cortisol concentrations and the testosterone-to-cortisol ratio: a preliminary study.

Katsuhiko Tsunekawa, Yoshifumi Shoho, Kazumi Ushiki, Yoshimaro Yanagawa, Ryutaro Matsumoto, Nozomi Shimoda, Tomoyuki Aoki, Akihiro Yoshida, Kiyomi Nakajima, Takao Kimura and 1 more

Erratum issuedOpen access · goldAbstract read
In one paragraph

Article in Scientific reports, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.0field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 7 citations in OpenAlex.

  1. Article
  2. High-speed resistance training vs. low-speed resistance training on body composition and physical function in adults with sarcopenic obesity.European review of aging and physical activity : official journal of the European Group for Research into Elderly and Physical Activity · 2026
    Article
  3. Article
  4. Article
  5. Endocrine regulation of circadian rhythms.Npj biological timing and sleep · 2025
    Review
  6. Review
  7. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

11 authors at 2 institutions in 1 country.

Katsuhiko TsunekawaDepartment of Clinical Laboratory Medicine, Gunma University Graduate School of Medicine, 3-39-22 Showa-machi, Maebashi, Gunma, 371-8511, Japan. ktsune@gunma-u.ac.jp.
Yoshifumi ShohoFaculty of Education, Ikuei University, 1656-1 Kyome-machi, Takasaki, Gunma, 370-0011, Japan.
Kazumi UshikiDepartment of Clinical Laboratory Medicine, Gunma University Graduate School of Medicine, 3-39-22 Showa-machi, Maebashi, Gunma, 371-8511, Japan.
Yoshimaro YanagawaFaculty of Education, Ikuei University, 1656-1 Kyome-machi, Takasaki, Gunma, 370-0011, Japan.
Ryutaro MatsumotoFaculty of Education, Ikuei University, 1656-1 Kyome-machi, Takasaki, Gunma, 370-0011, Japan.
Nozomi ShimodaDepartment of Clinical Laboratory Medicine, Gunma University Graduate School of Medicine, 3-39-22 Showa-machi, Maebashi, Gunma, 371-8511, Japan.
Tomoyuki AokiDepartment of Clinical Laboratory Medicine, Gunma University Graduate School of Medicine, 3-39-22 Showa-machi, Maebashi, Gunma, 371-8511, Japan.
Akihiro YoshidaDepartment of Clinical Laboratory Medicine, Gunma University Graduate School of Medicine, 3-39-22 Showa-machi, Maebashi, Gunma, 371-8511, Japan.
Kiyomi NakajimaDepartment of Clinical Laboratory Medicine, Gunma University Graduate School of Medicine, 3-39-22 Showa-machi, Maebashi, Gunma, 371-8511, Japan.
Takao KimuraDepartment of Clinical Laboratory Medicine, Gunma University Graduate School of Medicine, 3-39-22 Showa-machi, Maebashi, Gunma, 371-8511, Japan.
Masami MurakamiDepartment of Clinical Laboratory Medicine, Gunma University Graduate School of Medicine, 3-39-22 Showa-machi, Maebashi, Gunma, 371-8511, Japan.
Gunma University · JPIkuei Junior College · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In this study, our aim was to validate whether the automated measurement of salivary testosterone and cortisol concentrations and the testosterone-to-cortisol (T/C) ratio, considering their individual circadian rhythms can be used to assess the stress response of male athletes to different exercise intensities accurately and effectively. We measured the salivary testosterone and cortisol concentrations and their respective serum concentrations that were collected from 20 male long-distance runners via passive drooling in the morning and evening for two consecutive days involving different exercise intensities. An electrochemiluminescence immunoassay was performed to evaluate the salivary testosterone and cortisol concentrations. The results showed a positive correlation between the salivary testosterone and cortisol concentrations and their respective serum concentrations. The participants were divided into two groups: with and without interval training. The interval training group showed a significantly higher rate of change in the salivary cortisol concentration and a significantly lower rate of change in the T/C ratio in the evening interval training on day 1 than lower-intensity running on day 2. Our results indicated that the salivary cortisol concentrations and the T/C ratio could distinguish between exercises at different intensities, which may be beneficial for detecting differences in stress responses among athletes.

Indexed as

ExerciseHydrocortisoneSalivaStress, PhysiologicalTestosteroneAthletesAutomationCircadian RhythmHumansMaleRunningSialorrheaYoung AdultHydrocortisoneTestosterone

Identifiers

PMID37666925
PMCPMC10477232
OpenAlexW4386422033

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.