Evidence map›Paper›PMID 37666236›Full record

SynthesisPsychotherapy and psychosomatics2023

Allostatic Load in Children and Adolescents: A Systematic Review.

Marcella Lucente, Jenny Guidi

Abstract readSystematic Review
In one paragraph

Synthesis in Psychotherapy and psychosomatics, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

25 citing papers in PubMed.

  1. Trial
  2. Longitudinal associations between authoritarian parenting and adolescent antisocial thinking, depression, and anxiety: Between- and within-person effects.Journal of research on adolescence : the official journal of the Society for Research on Adolescence · 2026
    Article
  3. Review
  4. Observational
  5. Article
  6. Article
  7. Review
  8. Article
  9. Article
  10. Review
  11. Review
  12. Article
  13. Article
  14. Article
  15. Childhood allostatic load predicts cardiometabolic health in adulthood.Proceedings of the National Academy of Sciences of the United States of America · 2025
    Article
  16. Article
  17. Article
  18. Race and Ethnicity Moderates the Relationship Between Family Income Level and Allostatic Load Among Adolescents in the United States.The Journal of adolescent health : official publication of the Society for Adolescent Medicine · 2025
    Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Marcella LucenteDepartment of Psychology "Renzo Canestrari", University of Bologna, Bologna, Italy.
Jenny GuidiDepartment of Psychology "Renzo Canestrari", University of Bologna, Bologna, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionThe concept of allostatic load encompasses the cumulative effects of both ordinary daily life events as well as major challenges, and also includes related health-damaging behavior. Allostatic overload ensues when environmental challenges exceed the individual's ability to cope. Identification of allostatic load is carried out through the use of biomarkers and clinimetric criteria. Studies are increasingly reported on allostatic load in younger populations, yet a systematic review is missing.

objectiveThe aim of the present systematic review was to summarize the current knowledge on allostatic load/overload among children and adolescents.

methodsPubMed, PsycINFO, Web of Science, and the Cochrane Library were searched from inception to April 2023. A manual search of the literature was also performed. We considered only studies in which allostatic load or overload were adequately described and assessed in either clinical or non-clinical populations younger than 18 years.

resultsA total of 38 original investigations were included in this systematic review. Studies reported an association between allostatic load and sociodemographic characteristics (e.g., poverty, ethnicity, perceived discrimination, adverse childhood experiences) and environmental factors, as well as consequences of allostatic load on both physical and mental health among children and adolescents.

conclusionsThe findings indicate that greater allostatic load is associated with poorer health outcomes in both clinical and non-clinical pediatric populations, with possible enduring effects. The results support the clinical utility of the transdiagnostic identification of allostatic load and overload in children and adolescents across a variety of settings, with a number of potential clinical implications.

Indexed as

AllostasisAdolescentBiomarkersChildHumansMental HealthBiomarkersAdolescenceAllostatic loadAllostatic overloadBiomarkersChildhoodClinimetricsDiagnostic criteria for psychosomatic research

Identifiers

PMID37666236
PMCPMC10716875

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.