Evidence map›Paper›PMID 37666211›Full record

ArticleAIDS care2024

Childhood sexual abuse and antiretroviral therapy adherence among older adults living with HIV: a mixed methods study.

Monique J Brown, Titilayo James, Amandeep Kaur, Prince Nii Ossah Addo, Chigozie A Nkwonta, Nathan B Hansen, Anthony J Onwuegbuzie

Abstract read
In one paragraph

Article in AIDS care, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Childhood Sexual Trauma, Substance Use, and Antiretroviral Therapy Adherence Among Older Adults Living With HIV: A Mediational Analysis.Journal of applied gerontology : the official journal of the Southern Gerontological Society · 2025
    Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Monique J BrownDepartment of Epidemiology and Biostatistics, Arnold School of Public Health, University of South Carolina, Columbia, SC, USA.ORCID 0000-0001-9552-244X
Titilayo JamesDepartment of Epidemiology and Biostatistics, Arnold School of Public Health, University of South Carolina, Columbia, SC, USA.
Amandeep KaurDepartment of Epidemiology and Biostatistics, Arnold School of Public Health, University of South Carolina, Columbia, SC, USA.
Prince Nii Ossah AddoDepartment of Epidemiology and Biostatistics, Arnold School of Public Health, University of South Carolina, Columbia, SC, USA.
Chigozie A NkwontaRory Meyers College of Nursing, New York University, New York, NY, USA.
Nathan B HansenHealth Promotion and Behavior, College of Public Health, University of Georgia, Athens, Georgia.
Anthony J OnwuegbuzieFaculty of Education, University of Cambridge, Cambridge, England.

Funding

Developing a trauma-focused intervention for older adults living with HIVK01MH115794 · NIMH · UNIVERSITY OF SOUTH CAROLINA AT COLUMBIA · PI BROWN, MONIQUE JANIEL · 2018 to 2023
$657k
NIMH NIH HHS K01 MH115794
6 · The paper itself

Abstract

Findings on the association between childhood sexual abuse (CSA) and antiretroviral therapy (ART) adherence have been varied, with some studies showing a relationship, or a lack thereof. However, to our knowledge, no study has examined this association among older adults living with HIV (OALH). Therefore, the purpose of this study was to examine the association between CSA and ART adherence among OALH using a mixed methods approach. This study, which involved a concurrent design, had two phases. The first phase comprised in-depth, semi-structured interviews of 24 adults aged 50 and older living with HIV in South Carolina. The second phase included data from 91 OALH. Thematic analysis and multivariable regression models, adjusting for age, gender, race, and income, were used to determine the association between CSA and ART adherence. The main theme emerging from the qualitative data was that CSA was not linked with ART adherence. However, contrastingly, quantitative analyses revealed a negative statistically significant association between CSA and ART adherence (adjusted β: -3.35; 95% CI: -5.37, -1.34). This difference in findings could be due to the hidden impact of trauma and/or the use of different study populations. Future research should assess mediating pathways between CSA and ART adherence.

Indexed as

HIV InfectionsSex OffensesAgedAnti-Retroviral AgentsChildGender IdentityHumansMedication AdherenceMiddle AgedAnti-Retroviral AgentsART adherenceChildhood sexual abusemixed methodsolder adultsqualitative

Identifiers

PMID37666211
PMCPMC10841262

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.