ArticleSeminars in arthritis and rheumatism2023
Trends in adverse pregnancy outcomes among women with systemic sclerosis in the United States.
Article in Seminars in arthritis and rheumatism, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
4 citing papers in PubMed, 5 citations in OpenAlex.
- Association between pregnancy outcomes prior to diagnosis and clinical characteristics following diagnosis in patients with systemic sclerosis.Clinical rheumatology · 2026Article
- Association of Substance Use and Psychological Conditions With Adverse Pregnancy Outcomes: A Propensity-Matched Analysis.JACC. Advances · 2026Article
- Pregnancy outcomes in systemic sclerosis before and after diagnosis: a retrospective nationwide cohort study.Turkish journal of medical sciences · 2026Observational
- Pregnancy Outcomes in Women With Systemic Sclerosis Before and/or After Diagnosis and by Parity: A Swedish Population-Based Cohort Study.Arthritis & rheumatology (Hoboken, N.J.) · 2026Article
Corrections and comments
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Authors and funding
5 authors at 4 institutions in 1 country.
Funding
Abstract
objectivesWe sought to examine temporal trends in adverse pregnancy outcomes among SSc pregnancies in a large nationwide sample.
methodsWe used the National Inpatient Sample (NIS) database from 2000 - 2017 to derive national estimates of delivery-associated hospitalizations in the United States among patients with SSc. Each SSc delivery was matched to 100 non-SSc deliveries by age, delivery year, and race. We evaluated adverse pregnancy outcomes (APOs) including maternal and fetal death, cesarean delivery, hospital length of stay, preterm delivery, intrauterine growth restriction, and hypertensive disorders of pregnancy. We used multivariable regression models with an interaction term between SSc and year and adjusting for race, advanced maternal age, diabetes mellitus, and pre-existing hypertension to evaluate temporal trends in APOs among SSc and non-SSc deliveries.
resultsFrom 2000 to 2017, there were 3740 delivery-associated hospitalizations for women with SSc. SSc was associated with an increased risk of all APOs compared to non-SSc deliveries. Fetal death declined in SSc deliveries from 49.0 per 1000 delivery-related admissions in 2000 - 2005 to 16.2 per 1000 in 2012 - 2017. There was a significant difference in trends for fetal death between SSc and non-SSc deliveries (p = 0.043), but the trends for other APOs did not differ between the two groups.
conclusionsIn this large nationwide sample, the risk of fetal death among women with SSc markedly improved over the past 18 years. The risk for other APOs remained high in SSc deliveries compared to non-SSc deliveries, and further studies are needed to determine what strategies can improve these outcomes.
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