Evidence map›Paper›PMID 37666091›Full record

ArticleDrug and alcohol dependence2023

Applied risk mapping and spatial analysis of address-level decedent data to inform opioid overdose interventions: The Massachusetts HEALing Communities Study.

Jennifer Pustz, Sumeeta Srinivasan, Shikhar Shrestha, Marc R Larochelle, Alexander Y Walley, Jeffrey H Samet, Hermik Babakhanlou-Chase, Jane F Carpenter, Thomas J Stopka

Registry-linked trialAbstract read
In one paragraph

Article in Drug and alcohol dependence, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07528846 (Justice Community Overdose Innovation Network II TCU Hub), which is not on this map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT07528846 nanot yet recruitingnot on this mapstarted 2026, after this paper: background citation

Justice Community Overdose Innovation Network II TCU Hub: TCU Building Resilient Initiatives for Deflection Through Greater Engagement Project (TCU BRIDGE to Deflection Project)

TypeinterventionalSponsorTexas Christian UniversityRan2026 to 2029Enrolled1,620ConditionsSubstance Use Disorder (SUD), Drug Overdose, Criminal BehaviorArmsCore-interagency community engagement approach, Enhanced-Core plus community engagement specialist
3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Jennifer PustzDepartment of Public Health and Community Medicine, Tufts University School of Medicine, Boston, MA, USA. Electronic address: Jennifer.Pustz@tufts.edu.
Sumeeta SrinivasanDepartment of Urban and Environmental Policy and Planning, Tufts University, Medford, MA, USA.
Shikhar ShresthaDepartment of Public Health and Community Medicine, Tufts University School of Medicine, Boston, MA, USA.
Marc R LarochelleGrayken Center for Addiction, Clinical Addiction Research and Education Unit, Section of General Internal Medicine, Department of Medicine, Boston University Chobanian and Avedisian School of Medicine, Boston, MA, USA.
Alexander Y WalleyGrayken Center for Addiction, Clinical Addiction Research and Education Unit, Section of General Internal Medicine, Department of Medicine, Boston University Chobanian and Avedisian School of Medicine, Boston, MA, USA; Massachusetts Department of Public Health, Boston, MA, USA.
Jeffrey H SametGrayken Center for Addiction, Clinical Addiction Research and Education Unit, Section of General Internal Medicine, Department of Medicine, Boston University Chobanian and Avedisian School of Medicine, Boston, MA, USA; Department of Community Health Sciences, Boston University School of Public Health, Boston, MA, USA.
Hermik Babakhanlou-ChaseMassachusetts Department of Public Health, Boston, MA, USA.
Jane F CarpenterBoston Medical Center, Boston, MA,  USA.
Thomas J StopkaDepartment of Public Health and Community Medicine, Tufts University School of Medicine, Boston, MA, USA.

Funding

MassHEAL - Reducing overdose deaths by 40% (2019-2023)UM1DA049412 · NIDA · BOSTON MEDICAL CENTER · PI SAMET, JEFFREY H. · 2019 to 2023
$82.9M
NIDA NIH HHS UM1 DA049412
6 · The paper itself

Abstract

backgroundDeath certificate data provide powerful and sobering records of the opioid overdose crisis. In Massachusetts, where address-level decedent data are publicly available upon request, mapping and spatial analysis of fatal overdoses can provide valuable insights to inform prevention interventions. We describe how we used this approach to support a community-level intervention to reduce opioid-involved overdose mortality.

methodsWe developed a method to clean and geocode decedent data that substituted injury locations (the likely location of fatal overdoses) for deaths recorded in hospitals. After geomasking for greater privacy protection, we created maps to visualize the spatial distribution of decedent residence addresses, alone and juxtaposed with drive and walk-time distances to opioid treatment programs (OTPs), and place of death by overdose address. We used spatial statistical analyses to identify locations with significant clusters of overdoses.

resultsIn the 8 intervention communities, 785 individuals died from opioid-involved overdoses between 2017 and 2020. We found that 19.7% of fatal overdoses were recorded in hospitals, 50.2% occurred at the decedent's residence, and 30.1% at another location. We identified overdose hotspots in study communities. By juxtaposing decedent residence data with drive- and walk-time analyses, we highlighted actionable spatial gaps in access to OTP treatment.

conclusionTo better understand local fatal opioid overdose risk environments and inform the development of community-level prevention interventions, we used publicly available address-level decedent data to conduct nuanced spatial analyses. Our approach can be replicated in other jurisdictions to inform overdose prevention responses.

Indexed as

Opiate OverdoseSpatial AnalysisAdultDrug OverdoseFemaleHumansMaleMassachusettsMiddle AgedOpioid-Related DisordersYoung AdultMassachusettsOpioidsOverdoseSpatial analysisVital statistics

Identifiers

PMID37666091
PMCPMC10587829

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.