Evidence map›Paper›PMID 37666081›Full record

ArticleHormones and behavior2023

Determining menstrual cycle phase: An empirical examination of methodologies and recommendations for improvement in behavioral and brain sciences.

Lilianne M Gloe, Stefanie Russman Block, Kelly L Klump, Adriene M Beltz, Jason S Moser

Abstract read
In one paragraph

Article in Hormones and behavior, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed.

  1. Gendering the Menstrual Cycle in Behavioral Neuroendocrinology.American journal of human biology : the official journal of the Human Biology Council · 2026
    Review
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  13. Observational
  14. The link between daily affective complexity and anxiety is altered by oral contraceptive use.International journal of psychophysiology : official journal of the International Organization of Psychophysiology · 2024
    Article
  15. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Lilianne M GloeDepartment of Psychology, Michigan State University, East Lansing, MI 48823, USA; Department of Psychiatry and Psychology, Mayo Clinic, Rochester, MN 55905, USA. Electronic address: gloe.lilianne@mayo.edu.
Stefanie Russman BlockDepartment of Psychology, Michigan State University, East Lansing, MI 48823, USA; Department of Psychiatry, University of Michigan, Ann Arbor, MI 48109, USA.
Kelly L KlumpDepartment of Psychology, Michigan State University, East Lansing, MI 48823, USA.
Adriene M BeltzDepartment of Psychology, University of Michigan, Ann Arbor, MI 48109, USA.
Jason S MoserDepartment of Psychology, Michigan State University, East Lansing, MI 48823, USA.

Funding

A Twin Study of exogenous hormone exposure and risk for binge eatingR01MH111715 · NIMH · MICHIGAN STATE UNIVERSITY · PI KLUMP, KELLY L · 2017 to 2021
$4.0M
Cognitive Control in Anxiety: The Role of Ovarian HormonesR01MH108511 · NIMH · MICHIGAN STATE UNIVERSITY · PI MOSER, JASON SCOT · 2016 to 2020
$2.9M
NIMH NIH HHS R01 MH108511NIMH NIH HHS R01 MH111715
6 · The paper itself

Abstract

The recent decade has brought an exciting proliferation of behavioral, psychological and neuroscientific research involving the menstrual cycle. However, the reliability and validity of many popular methodologies for determining menstrual cycle phase lack empirical examination. These under-investigated methods include: (1) predicting menstrual cycle phase using self-report information only (e.g., "count" methods), (2) utilizing ovarian hormone ranges to determine menstrual cycle phase, and (3) using ovarian hormone changes from limited measurements (e.g., two time points) to determine menstrual cycle phase. In the current study, we examine the accuracy of these methods for menstrual cycle phase determination using 35-day within-person assessments of circulating ovarian hormones from 96 females across the menstrual cycle. Findings indicate that all three common methods are error-prone, resulting in phases being incorrectly determined for many participants, with Cohen's kappa estimates ranging from -0.13 to 0.53 indicating disagreement to only moderate agreement depending on the comparison. Such methodological challenges are surmountable through careful study design, more frequent hormone assays (when possible), and utilization of sophisticated statistical methods. With increased methodological rigor in behavioral, psychological and neuroscientific research, the field will be poised to detect biobehavioral correlates of ovarian hormone fluctuations for the betterment of the mental health and wellbeing of millions of females.

Indexed as

Menstrual CycleProgesteroneBrainEstradiolFemaleHumansReproducibility of ResultsEstradiolProgesteroneEstradiolMenstrual cycle phaseMethodologyOvarian hormone rangesOvarian hormonesProgesteroneSelf-report phase projection

Identifiers

PMID37666081
PMCPMC10714354

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.