ArticleMedical physics2023
A quantitative CBCT pipeline based on 2D antiscatter grid and grid-based scatter sampling for image-guided radiation therapy.
Article in Medical physics, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
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10 citing papers in PubMed, 10 citations in OpenAlex.
- Improving deep learning organ segmentation accuracy in cone-beam CT-guided radiotherapy using a robust scatter suppression method.Physics and imaging in radiation oncology · 2026Article
- A Dual-Energy CBCT With Reduced Scatter and Cone Beam Artifacts Using an X-Ray Source Array and Interlaced Spectral Filters.IEEE transactions on bio-medical engineering · 2026Article
- CBCT Dose Is Reduced with Angular Tube Current Modulation While Maintaining Image Quality and Reducing Photon Starvation Artifacts.Annals of biomedical engineering · 2026Article
- Deep learning-based multi-modality image conversion for evaluating dose calculation and position correction accuracy in image-guided radiation therapy.Radiological physics and technology · 2026Article
- Improving the robustness of radiomic features to patient size variations in CBCT imaging for radiotherapy.Journal of X-ray science and technology · 2026Article
- Effect of a prototype 2-dimensional antiscatter grid on image quality obtained with a dental cone-beam computed tomography scanner.Imaging science in dentistry · 2025Article
- Investigation of 2D anti-scatter grid implementation in a gantry-mounted cone beam computed tomography system for proton therapy.Physics and imaging in radiation oncology · 2025Article
- Evaluation of a compact cone beam CT concept with high image fidelity for point-of-care brain imaging.Scientific reports · 2024Article
- 2D antiscatter grid and scatter sampling based CBCT method for online dose calculations during CBCT guided radiation therapy of pelvis.Medical physics · 2024Article
- 3D Digital Modeling of Dental Casts from Their 3D CT Images with Scatter and Beam-Hardening Correction.Sensors (Basel, Switzerland) · 2024Article
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Authors and funding
4 authors at 2 institutions in 1 country.
Funding
Abstract
backgroundQuantitative accuracy is critical for expanding the role of cone beam CT (CBCT) imaging from target localization to quantitative treatment monitoring and plan adaptations in radiation therapy. Despite advances in CBCT image quality improvement methods, quantitative accuracy gap between CBCT and multi-detector CT (MDCT) remains. PURPOSE: In this work, a physics-driven approach was investigated that combined robust scatter rejection, raw data correction and iterative image reconstruction to further improve CBCT image quality and quantitative accuracy, referred to as quantitative CBCT (qCBCT).
methodsQCBCT approach includes tungsten 2D antiscatter grid hardware, residual scatter correction with grid-based scatter sampling, image lag, and beam hardening correction for offset detector geometry linac-mounted CBCT. Images were reconstructed with iterative image reconstruction to reduce image noise. qCBCT was evaluated using a variety of phantoms to investigate the effect of object size and its composition on image quality, and image quality was benchmarked against clinical CBCT and gold standard MDCT images used for treatment planning.
resultsQCBCT provided statistically significant improvement in CT number accuracy and reduced image artifacts when compared to clinical CBCT images. When compared to gold standard MDCT, mean HU errors in qCBCT and clinical CBCT were 17 ± 9 and 38 ± 29 HU, respectively. Magnitude of phantom size dependent HU variations were comparable between MDCT and qCBCT images. With iterative reconstruction, contrast-to-noise ratio improved by 25% when compared to clinical CBCT protocols.
conclusionsCombination of novel scatter suppression techniques and other data correction methods in qCBCT provided CT number accuracy comparable to gold standard MDCT used for treatment planning. This approach may potentially improve CBCT's promise in fulfilling the tasks that demand high quantitative accuracy, such as online dose calculations and treatment response assessment, in image guided radiation therapy.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.