Evidence map›Paper›PMID 37665390›Full record

ArticleEuropean radiology2024

Role of dynamic contrast-enhanced MRI in predicting severe acute radiation-induced rectal injury in patients with rectal cancer.

Yan Chen, Li Ding, Zhi-Wen Zhang, Xue-Han Wu, Yu-Tao Que, Yu-Ru Ma, Yi-Yan Liu, Zi-Qiang Wen, Xin-Yue Yang, Bao-Lan Lu and 3 more

Abstract read
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In one paragraph

Article in European radiology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
1.4field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 6 citations in OpenAlex.

  1. Article
  2. Article
  3. Salivary gland pathologies: evolution in classification and association with unique genetic alterations.European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery · 2023
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 2 institutions in 1 country.

Yan Chen *Department of Radiology, The First Affiliated Hospital, Sun Yat-Sen University, Guangzhou, 510080, China.
Li Ding *Department of Pathology, The First Affiliated Hospital, Sun Yat-Sen University, Guangzhou, 510080, China.
Zhi-Wen ZhangDepartment of Radiology, The First Affiliated Hospital, Sun Yat-Sen University, Guangzhou, 510080, China.
Xue-Han WuDepartment of Radiology, The First Affiliated Hospital, Sun Yat-Sen University, Guangzhou, 510080, China.
Yu-Tao QueDepartment of Radiology, The First Affiliated Hospital, Sun Yat-Sen University, Guangzhou, 510080, China.
Yu-Ru MaDepartment of Radiology, The First Affiliated Hospital, Sun Yat-Sen University, Guangzhou, 510080, China.
Yi-Yan LiuDepartment of Radiology, The First Affiliated Hospital, Sun Yat-Sen University, Guangzhou, 510080, China.
Zi-Qiang WenDepartment of Radiology, The First Affiliated Hospital, Sun Yat-Sen University, Guangzhou, 510080, China.
Xin-Yue YangDepartment of Radiology, Zhujiang Hospital, Southern Medical University, Guangzhou, 510280, China.
Bao-Lan LuDepartment of Radiology, The First Affiliated Hospital, Sun Yat-Sen University, Guangzhou, 510080, China.
Yong BaoDepartment of Radiotherapy, The First Affiliated Hospital, Sun Yat-Sen University, Guangzhou, 510080, China.
Shao-Qing NiuDepartment of Radiotherapy, The First Affiliated Hospital, Sun Yat-Sen University, Guangzhou, 510080, China. niushq5@mail.sysu.edu.cn.
Shen-Ping YuDepartment of Radiology, The First Affiliated Hospital, Sun Yat-Sen University, Guangzhou, 510080, China. yushp@mail.sysu.edu.cn.ORCID http://orcid.org/0000-0002-5988-781X
Sun Yat-sen University · CNZhujiang Hospital · CN

Funding

Guangdong Basic and Applied Basic Research Foundation 2020A1515010796
6 · The paper itself

Abstract

objectivesTo explore the potential of dynamic contrast-enhanced MRI (DCE-MRI) quantitative parameters in predicting severe acute radiation-induced rectal injury (RRI) in rectal cancer.

methodsThis retrospective study enrolled 49 patients with rectal cancer who underwent neoadjuvant chemoradiotherapy and rectal MRI including a DCE-MRI sequence from November 2014 to March 2021. Two radiologists independently measured DCE-MRI quantitative parameters, including the forward volume transfer constant (K

resultsForty-nine patients (mean age, 54 years ± 12 [standard deviation]; 37 men) were enrolled, including 25 patients with severe acute RRI. K

conclusionK CLINICAL RELEVANCE STATEMENT: Dynamic contrast-enhanced MRI can provide non-invasive and objective evidence for perioperative management and treatment strategies in rectal cancer patients with acute radiation-induced rectal injury. KEY POINTS: • To our knowledge, this study is the first to evaluate the predictive value of contrast-enhanced MRI (DCE-MRI) quantitative parameters for severe acute radiation-induced rectal injury (RRI) in patients with rectal cancer. • Forward volume transfer constant (K

Indexed as

Contrast MediaRectal NeoplasmsHumansMagnetic Resonance ImagingMaleMiddle AgedRectumRetrospective StudiesContrast MediaMagnetic resonance imagingNeoadjuvant therapyPerfusion imagingRadiation injuriesRectal neoplasms

Identifiers

PMID37665390
OpenAlexW4386407108

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.