ArticleJournal of periodontology2024
Impact of surface characteristics on the peri-implant microbiome in health and disease.
Article in Journal of periodontology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
16 citing papers in PubMed, 21 citations in OpenAlex.
- Bone stability after regenerative peri-implantitis treatment: A 10-year follow-up case study.Clinical advances in periodontics · 2026Article
- Balancing Osseointegration and Infection Control: The Role of Titanium Surface Topography in Peri-Implant Biology.Journal of functional biomaterials · 2026Article
- Peri-Implantitis and Periodontitis: Biological Convergence, Contextual Divergence.Journal of periodontal research · 2026Review
- Impact of OMICS Technologies in Our Understanding of the Pathogenesis of Peri-Implantitis.Clinical and experimental dental research · 2026Review
- Establishment of a three-dimensional in vitro peri-implant bone-mucosa composite model.BMC oral health · 2026Article
- Clinical factors associated with peri-implantitis and the culture-based microbiological profile of peri-implantitis cases: a retrospective matched case-control study.Frontiers in cellular and infection microbiology · 2026Article
- Peri-implantitis progression and modulating factors: evidence synthesis and implications for clinical management.Brazilian oral research · 2026Review
- Peri-implantitis biofilm from explanted implants in Korean patients: microbial and functional profiling.Frontiers in cellular and infection microbiology · 2026Article
- Pathobiology of ESKAPE Biofilms in implant infections: current understanding and implications for future therapeutic strategies.Frontiers in cellular and infection microbiology · 2026Review
- Community dynamics during de novo colonization of the nascent peri-implant sulcus.International journal of oral science · 2025Article
- Vitamin D3-Coated Surfaces and Their Role in Bone Repair and Peri-Implant Biomechanics.Biology · 2025Article
- Long-Term Clinical Study on Sandblasted-Acid-Etched Surface Dental Implants: 12-Year Follow-Up.Materials (Basel, Switzerland) · 2025Article
- Influence of species composition and cultivation condition on peri-implant biofilm dysbiosisFrontiers in oral health · 2025Article
- Linking peri-implantitis to microbiome changes in affected implants, healthy implants, and saliva: a cross-sectional pilot study.Frontiers in cellular and infection microbiology · 2025Article
- The Oral Microbiome of Peri-Implant Health and Disease: A Narrative Review.Dentistry journal · 2024Review
- Advances in biomaterials for oral-maxillofacial bone regeneration: spotlight on periodontal and alveolar bone strategies.Regenerative biomaterials · 2024Review
Corrections and comments
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Authors and funding
6 authors at 2 institutions in 1 country.
Funding
Abstract
backgroundBecause little is known about the impact of implant surface modifications on the peri-implant microbiome, we aimed to examine peri-implant communities in various surface types in order to better understand the impact of these surfaces on the development of peri-implantitis (PI).
methodsOne hundred and six systemically healthy individuals with anodized (AN), hydroxyapatite-coated (HA), or sandblasted acid-etched (SLA) implants that were >6 months in function were recruited and categorized into health (H) or PI. Peri-implant biofilm was analyzed using 16S rRNA gene sequencing and compared between health/disease and HA/SLA/AN using community-level and taxa-level metrics.
resultsHealthy implants did not demonstrate significant differences in clustering, alpha- or beta-diversity based on surface modification. AN and HA surfaces displayed significant differences between health and PI (p < 0.05); however, such a clustering was not evident with SLA (p > 0.05). AN and HA surfaces also differed in the magnitude and diversity of differences between health and PI. Six species belonging to the genera Shuttleworthia, Scardovia, and Prevotella demonstrated lower abundances in AN implants with PI, and 18 species belonging to the genera Fretibacterium, Tannerella, Treponema, and Fusobacterium were elevated, while in HA implants with PI, 20 species belonging to the genera Streptococcus, Lactobacillus, Veillonella, Rothia, and family Ruminococcaceae were depleted and Peptostreptococcaceae, Atopobiaceae, Veillonellaceae, Porphyromonadaceae, Desulfobulbaceae, and order Synergistales were enriched.
conclusionsWithin the limitations of this study, we demonstrate that implant surface can differentially modify the disease-associated microbiome, suggesting that surface topography must be considered in the multi-factorial etiology of peri-implant diseases.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.