ArticleDento maxillo facial radiology2023
Differentiation between pleomorphic adenoma and schwannoma in the parapharyngeal space: histogram analysis of apparent diffusion coefficient.
Article in Dento maxillo facial radiology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.
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Who cites it
6 citing papers in PubMed, 5 citations in OpenAlex.
- Ultrasound-guided percutaneous fine-needle aspiration in parapharyngeal space lesions: a critical appraisal with illustrative cases.Gland surgery · 2026Review
- Parapharyngeal Schwannoma: Limitations Regarding Diagnosis and Surgical Intervention-A Case Report and Focused Literature Review.Diagnostics (Basel, Switzerland) · 2026Article
- Pleomorphic adenoma of the parapharyngeal space: a case report.Journal of medical case reports · 2026Article
- Performance of Routine MRI Reporting for Parapharyngeal Space Tumors: A Retrospective Radiologic-Pathologic Comparison.Journal of clinical medicine · 2026Article
- Sinonasal adenoid cystic carcinoma: preoperative apparent diffusion coefficient histogram analysis in prediction of prognosis and Ki-67 proliferation status.Japanese journal of radiology · 2025Article
- Evaluation of multiparametric MRI differentiating pleomorphic adenoma from schwannoma in parapharyngeal space.European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery · 2024Article
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Authors and funding
5 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectivesTo elucidate the differences between pleomorphic adenomas and schwannomas occurring in the parapharyngeal space by histogram analyses of apparent diffusion coefficient (ADC) values measured with diffusion-weighted MRI.
methodsThis retrospective study included 29 patients with pleomorphic adenoma and 22 patients with schwannoma arising in the parapharyngeal space or extending into the parapharyngeal space from the parotid region. Using pre-operative MR images, ADC values of tumor lesions showing the maximum diameter were measured. The regions of interest for ADC measurement were placed by contouring the tumor margin, and the histogram metrics of ADC values were compared between pleomorphic adenomas and schwannomas regarding the mean, skewness, and kurtosis by Wilcoxon's rank sum test. Subsequent to the primary analysis which included all lesions, we performed two subgroup analyses regarding b-values and magnetic field strength used for MRI.
resultsThe mean ADC values did not show significant differences between pleomorphic adenomas and schwannomas for the primary and subgroup analyses. Schwannomas showed higher skewness (
conclusionsSkewness and kurtosis showed significant differences between pleomorphic adenomas and schwannomas occupying the parapharyngeal space, but the mean ADC values did not. Our results suggest that the skewness and kurtosis of ADC histograms may be useful in differentiating these two parapharyngeal tumors.
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