Evidence map›Paper›PMID 37664991›Full record

ArticleEpidemiology and infection2023

Understanding the leading indicators of hospital admissions from COVID-19 across successive waves in the UK.

Jonathon Mellor, Christopher E Overton, Martyn Fyles, Liam Chawner, James Baxter, Tarrion Baird, Thomas Ward

Abstract read
In one paragraph

Article in Epidemiology and infection, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Review
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Jonathon MellorUK Health Security Agency, Data, Analytics and Surveillance, Nobel House, London, UK.
Christopher E OvertonUK Health Security Agency, Data, Analytics and Surveillance, Nobel House, London, UK.
Martyn FylesUK Health Security Agency, Data, Analytics and Surveillance, Nobel House, London, UK.
Liam ChawnerUK Health Security Agency, Data, Analytics and Surveillance, Nobel House, London, UK.
James BaxterUK Health Security Agency, Data, Analytics and Surveillance, Nobel House, London, UK.
Tarrion BairdUK Health Security Agency, Data, Analytics and Surveillance, Nobel House, London, UK.
Thomas WardUK Health Security Agency, Data, Analytics and Surveillance, Nobel House, London, UK.ORCID 0000-0001-8801-747X

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Following the end of universal testing in the UK, hospital admissions are a key measure of COVID-19 pandemic pressure. Understanding leading indicators of admissions at the National Health Service (NHS) Trust, regional and national geographies help health services plan for ongoing pressures. We explored the spatio-temporal relationships of leading indicators of hospitalisations across SARS-CoV-2 waves in England. This analysis includes an evaluation of internet search volumes from Google Trends, NHS triage calls and online queries, the NHS COVID-19 app, lateral flow devices (LFDs), and the ZOE app. Data sources were analysed for their feasibility as leading indicators using Granger causality, cross-correlation, and dynamic time warping at fine spatial scales. Google Trends and NHS triages consistently temporally led admissions in most locations, with lead times ranging from 5 to 20 days, whereas an inconsistent relationship was found for the ZOE app, NHS COVID-19 app, and LFD testing, which diminished with spatial resolution, showing cross-correlation of leads between -7 and 7 days. The results indicate that novel surveillance sources can be used effectively to understand the expected healthcare burden within hospital administrative areas though the temporal and spatial heterogeneity of these relationships is a key determinant of their operational public health utility.

Indexed as

COVID-19EnglandHospitalizationHospitalsHumansPandemicsSARS-CoV-2State MedicineCOVID-19healthcare pressureHospitalisationleading indicatorsSyndromic surveillance

Identifiers

PMID37664991
PMCPMC10600913

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.