Evidence map›Paper›PMID 37664610›Full record

ArticleiScience2023

M E Cicardi, J H Hallgren, D Mawrie, K Krishnamurthy, S S Markandaiah, A T Nelson, V Kankate, E N Anderson, P Pasinelli, U B Pandey and 2 more

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in iScience, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
2.5field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 12 citations in OpenAlex.

  1. Article
  2. Review
  3. Review
  4. Fibrillarin: bridging ribosome biogenesis and apoptosis in cellular stress and disease.Apoptosis : an international journal on programmed cell death · 2026
    Review
  5. Article
  6. Review
  7. Targeting GeneInternational journal of molecular sciences · 2025
    Review
  8. Article
  9. Review
  10. Article
  11. Review
  12. Article
4 · The record

Corrections and comments

  • Update of
    2023
5 · Who and what money

Authors and funding

12 authors at 2 institutions in 1 country.

M E CicardiWeinberg ALS Center, Vickie and Jack Farber Institute for Neuroscience, Department of Neuroscience, Thomas Jefferson University, Philadelphia, PA, USA.
J H HallgrenWeinberg ALS Center, Vickie and Jack Farber Institute for Neuroscience, Department of Neuroscience, Thomas Jefferson University, Philadelphia, PA, USA.
D MawrieCenter for Neuroscience, Department of Human Genetics, University of Pittsburgh Graduate School of Public Health, Pittsburgh, PA, USA.
K KrishnamurthyWeinberg ALS Center, Vickie and Jack Farber Institute for Neuroscience, Department of Neuroscience, Thomas Jefferson University, Philadelphia, PA, USA.
S S MarkandaiahWeinberg ALS Center, Vickie and Jack Farber Institute for Neuroscience, Department of Neuroscience, Thomas Jefferson University, Philadelphia, PA, USA.
A T NelsonWeinberg ALS Center, Vickie and Jack Farber Institute for Neuroscience, Department of Neuroscience, Thomas Jefferson University, Philadelphia, PA, USA.
V KankateWeinberg ALS Center, Vickie and Jack Farber Institute for Neuroscience, Department of Neuroscience, Thomas Jefferson University, Philadelphia, PA, USA.
E N AndersonCenter for Neuroscience, Department of Human Genetics, University of Pittsburgh Graduate School of Public Health, Pittsburgh, PA, USA.
P PasinelliWeinberg ALS Center, Vickie and Jack Farber Institute for Neuroscience, Department of Neuroscience, Thomas Jefferson University, Philadelphia, PA, USA.
U B PandeyCenter for Neuroscience, Department of Human Genetics, University of Pittsburgh Graduate School of Public Health, Pittsburgh, PA, USA.
C M EischenSidney Kimmel Cancer Center, Department of Pharmacology, Physiology, and Cancer Biology, Thomas Jefferson University, Philadelphia, PA, USA.
D TrottiWeinberg ALS Center, Vickie and Jack Farber Institute for Neuroscience, Department of Neuroscience, Thomas Jefferson University, Philadelphia, PA, USA.
Thomas Jefferson University · USUniversity of Pittsburgh · US

Funding

Exosome-mediated propagation of disease linked poly-dipeptides in C9orf72-FTD/ALSRF1AG057882 · NIA · THOMAS JEFFERSON UNIVERSITY · PI TROTTI, DAVIDE, YANG, YONGJIE · 2018 to 2018
$3.6M
Contribution of astrocytes to mutant FUS-linked Amyotrophic Lateral SclerosisR01NS109150 · NINDS · THOMAS JEFFERSON UNIVERSITY · PI PASINELLI, PIERA · 2019 to 2023
$1.7M
Development of a mouse model of C9ORF72 ALS/FTD expressing RAN translated peptideR21NS090912 · NINDS · THOMAS JEFFERSON UNIVERSITY · PI TROTTI, DAVIDE · 2014 to 2015
$428k
NIA NIH HHS RF1 AG057882NINDS NIH HHS R01 NS109150NINDS NIH HHS R21 NS090912
6 · The paper itself

Abstract

The ALS/FTD-linked intronic hexanucleotide repeat expansion in the

Indexed as

Cellular neuroscienceMolecular neuroscience

Identifiers

PMID37664610
PMCPMC10470315
OpenAlexW4385337127

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.