Evidence map›Paper›PMID 37664523›Full record

ArticleBiochemistry and biophysics reports2023

Socs1-knockout in skin-resident CD4

Yixin Luo, Maarten H Vermeer, Sanne de Haan, Priscilla Kinderman, Frank R de Gruijl, Thorbald van Hall, Cornelis P Tensen

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Biochemistry and biophysics reports, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.4field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Review
  5. "Next top" mouse models advancing CTCL research.Frontiers in cell and developmental biology · 2024
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Yixin LuoDepartment of Dermatology, Leiden University Medical Center, Leiden, the Netherlands.
Maarten H VermeerDepartment of Dermatology, Leiden University Medical Center, Leiden, the Netherlands.
Sanne de HaanDepartment of Dermatology, Leiden University Medical Center, Leiden, the Netherlands.
Priscilla KindermanDepartment of Gastroenterology and Hepatology, Leiden University Medical Center, Leiden, the Netherlands.
Frank R de GruijlDepartment of Dermatology, Leiden University Medical Center, Leiden, the Netherlands.
Thorbald van HallDepartment of Medical Oncology, Oncode Institute, Leiden University Medical Center, Leiden, the Netherlands.
Cornelis P TensenDepartment of Dermatology, Leiden University Medical Center, Leiden, the Netherlands.
Leiden University Medical Center · NL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Recent detailed genomic analysis of mycosis fungoides (MF) identified suppressor of cytokine signaling 1 (SOCS1), an inhibitor of JAK/STAT signaling, as one of the frequently deleted tumor suppressors in MF, and one-copy deletion of SOCS1 was confirmed in early-stage MF lesions. To better understand the functional role of SOCS1 in the genesis of MF, we used a genetically engineered mouse model emulating heterozygous SOCS1 loss in skin resident CD4

Indexed as

CD4+ T cellsInflammationMycosis fungoidesSocs1Transgenic mouse

Identifiers

PMID37664523
PMCPMC10470183
OpenAlexW4386062685

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.