Evidence map›Paper›PMID 37664441›Full record

ArticleLeukemia research reports2023

Early progression and transformation of a splenic diffuse red pulp small B-cell lymphoma with NOTCH1, ARID2, CREBBP, and TNFRSF14 gene mutations.

Paolo Lopedote, Ahmad Al Nawaiseh, Anita Malek, Garrey Faller, Mariana Hattar, Edward Dow, Olga Kozyreva

Open access · goldAbstract readCase Reports
In one paragraph

Article in Leukemia research reports, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.8field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 3 citations in OpenAlex.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 1 country.

Paolo LopedoteDepartment of Medicine, St Elizabeth's Medical Center, Boston University, Boston, MA, United States.
Ahmad Al NawaisehDepartment of Medicine, St Elizabeth's Medical Center, Boston University, Boston, MA, United States.
Anita MalekDepartment of Pathology, St Elizabeth's Medical Center, Boston, MA, United States.
Garrey FallerDepartment of Pathology, Good Samaritan Medical Center, Brockton, MA, United States.
Mariana HattarDepartment of Medicine, St Elizabeth's Medical Center, Boston University, Boston, MA, United States.
Edward DowNorfolk Center for Cancer Care, Brockton, MA, United States.
Olga KozyrevaDepartment of Medical Oncology, St Elizabeth's Medical Center, Dana Farber Cancer Institute, Boston, MA, United States.
Boston University · USSt. Elizabeth's Medical Center · USGood Samaritan Medical Center · USSignature Healthcare Brockton Hospital · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Splenic diffuse red pulp small B-cell lymphoma (SDRPL) is a rare entity. Diagnosis is typically achieved with splenectomy and most patients remain in remission after this intervention. Hemoglobin value less than 10 g/dL and NOTCH1, TP53, and MAP2K1 gene mutations at diagnosis have been associated with worse outcome. Progression after splenectomy of SDRPL is possible, although transformation to aggressive lymphoma has rarely been reported. We herein report the case of a patient formerly diagnosed with SDRPL with gene mutations involving CREBBP, NOTCH1, ARID2, and TNFRSF14 who transformed to diffuse large B-cell lymphoma six months after splenectomy.

Indexed as

Diffuse large B-cell lymphomaNGSRed pulp lymphomaSDRPLTransformed lymphoma

Identifiers

PMID37664441
PMCPMC10471916
OpenAlexW4386067359

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.