Evidence map›Paper›PMID 37664152›Full record

ArticleWorld journal of gastroenterology2023

Gastric cancer incidence based on endoscopic Kyoto classification of gastritis.

Osamu Toyoshima, Toshihiro Nishizawa, Shuntaro Yoshida, Tatsuya Matsuno, Gota Fujisawa, Akira Toyoshima, Hirotoshi Ebinuma, Mitsuhiro Fujishiro, Yutaka Saito, Hidekazu Suzuki

Open access · hybridAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in World journal of gastroenterology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed, 1 pooled it
2.9field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 1 synthesis or guideline pooled it, 9 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Helicobacter pylori Management in Older Adults: Current Perspectives From Japan.The Korean journal of helicobacter and upper gastrointestinal research · 2026
    Review
  4. Review
  5. Endoscopic Diagnosis of Early Gastric Cancer and High-Risk Gastritis.The Korean journal of helicobacter and upper gastrointestinal research · 2024
    Review
  6. Article
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 1 country.

Osamu ToyoshimaDepartment of Gastroenterology, Toyoshima Endoscopy Clinic, Tokyo 157-0066, Japan.
Toshihiro NishizawaDepartment of Gastroenterology and Hepatology, International University of Health and Welfare, Narita Hospital, Narita 286-8520, Japan. nisizawa@kf7.so-net.ne.jp.
Shuntaro YoshidaDepartment of Gastroenterology, Toyoshima Endoscopy Clinic, Tokyo 157-0066, Japan.
Tatsuya MatsunoDepartment of Gastroenterology, Toyoshima Endoscopy Clinic, Tokyo 157-0066, Japan.
Gota FujisawaDepartment of Gastroenterology, Toyoshima Endoscopy Clinic, Tokyo 157-0066, Japan.
Akira ToyoshimaDepartment of Colorectal Surgery, Japanese Red Cross Medical Center, Tokyo 150-8935, Japan.
Hirotoshi EbinumaDepartment of Gastroenterology and Hepatology, International University of Health and Welfare, Narita Hospital, Narita 286-8520, Japan.
Mitsuhiro FujishiroDepartment of Gastroenterology, Graduate School of Medicine, The University of Tokyo, Tokyo 113-8655, Japan.
Yutaka SaitoDivision of Endoscopy, National Cancer Center Hospital, Tokyo 104-0045, Japan.
Hidekazu SuzukiDivision of Gastroenterology and Hepatology, Department of Internal Medicine, Tokai University School of Medicine, Isehara 259-1193, Japan.
International University of Health and Welfare · JPThe University of Tokyo · JPTokai University · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundGastric cancer (GC) incidence based on the endoscopic Kyoto classification of gastritis has not been systematically investigated using time-to-event analysis.

aimTo examine GC incidence in an endoscopic surveillance cohort.

methodsThis study was retrospectively conducted at the Toyoshima Endoscopy Clinic. Patients who underwent two or more esophagogastroduodenoscopies were enrolled. GC incidence was based on Kyoto classification scores, such as atrophy, intestinal metaplasia (IM), enlarged folds (EFs), nodularity, diffuse redness (DR), and total Kyoto scores. Hazard ratios (HRs) adjusted for age and sex were calculated using a Cox hazard model.

resultsA total of 6718 patients were enrolled (median age 54.0 years; men 44.2%). During the follow-up period (max 5.02 years; median 2.56 years), GC developed in 34 patients. The average frequency of GCs per year was 0.19%. Kyoto atrophy scores 1 [HR with score 0 as reference: 3.66, 95% confidence interval (CI): 1.06 to 12.61], 2 (11.60, 3.82-35.27), IM score 2 (9.92, 4.37-22.54), EF score 1 (4.03, 1.63-9.96), DR scores 1 (6.22, 2.65-14.56), and 2 (10.01, 3.73-26.86) were associated with GC incidence, whereas nodularity scores were not. The total Kyoto scores of 4 (HR with total Kyoto scores 0-1 as reference: 6.23, 95%CI: 1.93 to 20.13,

conclusionA high total Kyoto score (≥ 4) was associated with GC incidence. The endoscopy-based diagnosis of gastritis can stratify GC risk.

Indexed as

GastritisStomach NeoplasmsAtrophyEndoscopyHumansIncidenceMaleMiddle AgedRetrospective StudiesAtrophyEndoscopyGastric cancerGastritisIntestinal metaplasiaKyoto classification

Identifiers

PMID37664152
PMCPMC10473921
OpenAlexW4385981522

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.