Evidence map›Paper›PMID 37664012›Full record

ArticleFrontiers in oncology2023

Lung cancer survival among Florida male firefighters.

Tulay Koru-Sengul, Paulo S Pinheiro, Wei Zhao, Monique N Hernandez, Diana R Hernandez, Alessandra Maggioni, Erin N Kobetz, Alberto J Caban-Martinez, David J Lee

Abstract read
In one paragraph

Article in Frontiers in oncology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Tulay Koru-SengulDepartment of Public Health Sciences, University of Miami, Leonard M. Miller School of Medicine, Miami, FL, United States.
Paulo S PinheiroDepartment of Public Health Sciences, University of Miami, Leonard M. Miller School of Medicine, Miami, FL, United States.
Wei ZhaoSylvester Comprehensive Cancer Center, University of Miami, Leonard M. Miller School of Medicine, Miami, FL, United States.
Monique N HernandezFlorida Cancer Data System, University of Miami, Leonard M. Miller School of Medicine, Miami, FL, United States.
Diana R HernandezDepartment of Public Health Sciences, University of Miami, Leonard M. Miller School of Medicine, Miami, FL, United States.
Alessandra MaggioniDepartment of Public Health Sciences, University of Miami, Leonard M. Miller School of Medicine, Miami, FL, United States.
Erin N KobetzDepartment of Public Health Sciences, University of Miami, Leonard M. Miller School of Medicine, Miami, FL, United States.
Alberto J Caban-MartinezDepartment of Public Health Sciences, University of Miami, Leonard M. Miller School of Medicine, Miami, FL, United States.
David J LeeDepartment of Public Health Sciences, University of Miami, Leonard M. Miller School of Medicine, Miami, FL, United States.

Funding

Tumor Biology Research ProgramP30CA240139 · NCI · UNIVERSITY OF MIAMI SCHOOL OF MEDICINE · PI Daniel Bilbao · 2019 to 2026
$24.1M
NCI NIH HHS P30 CA240139
6 · The paper itself

Abstract

Introduction: Lung cancer is a leading cause of cancer incidence and death in the United States. Although most firefighters are fit and do not smoke, they are exposed to many known carcinogens during and in the aftermath of firefighting activities. Comprehensive epidemiologic investigations on lung cancer survival for both career and volunteer firefighters have not been undertaken. Methods: Data from the Florida Cancer Data System (1981-2014) were linked with firefighter certification records from the Florida State Fire Marshal's Office to identify all patients of this occupational group; lung cancer cause-specific survival data were compared with other occupational groups using Cox regression models with occupation as the main effect. Adjusted hazard ratios (aHR) and 95% confidence intervals (95% CI) were calculated. Results: Out of 210,541 male lung cancer cases diagnosed in Florida (1981-2014), 761 were firefighters (604 career, 157 volunteer). Lung cancer death was similar between volunteer (75.2%) and career firefighters (74.0%) but lower than non-firefighters (80.0%). Survival at 5 years was higher among firefighters (29.7%; career: 30.3%; volunteer: 27.4%) than non-firefighters (23.8%). In a multivariable model, compared with non-firefighters, firefighters have significantly higher cause-specific survival (aHR = 0.84; 95% CI: 0.77-0.91; Conclusion: Lung cancer survival is significantly higher among firefighters compared with non-firefighters, but there is no significant difference between career and volunteer firefighters. Improved survival for firefighters might be due to a healthy worker effect, lower smoking prevalence relative to other worker groups, and possibly superior treatment adherence and compliance. Many firefighters are cross-trained as EMTs/paramedics and possess a level of medical knowledge that may favorably impact treatment engagement and better navigation of complex cancer care.

Indexed as

cancer survivalfirefightersFloridalung canceroccupational exposure

Identifiers

PMID37664012
PMCPMC10473410

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.