Evidence map›Paper›PMID 37663808›Full record

ArticleToxicology research2023

Study on the mechanism of PM2.5 affecting Th1/Th2 immune imbalance through the notch signaling pathway in asthmatic mice.

Ji-Rong Wu, Zheng He, Hai-Rong Bao, Xiao-Li Zeng, Xiao-Ju Liu

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Toxicology research, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.8field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 10 citations in OpenAlex.

  1. Review
  2. Review
  3. Article
  4. Particulate matter-induced epigenetic modifications and lung complications.European respiratory review : an official journal of the European Respiratory Society · 2024
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Ji-Rong WuDepartment of Grontal Respiratory Medicine, The First Hospital of Lanzhou University, Lanzhou 730000, China.ORCID https://orcid.org/0000-0003-4210-242X
Zheng HeDepartment of Grontal Respiratory Medicine, The First Hospital of Lanzhou University, Lanzhou 730000, China.
Hai-Rong BaoDepartment of Grontal Respiratory Medicine, The First Hospital of Lanzhou University, Lanzhou 730000, China.
Xiao-Li ZengDepartment of Grontal Respiratory Medicine, The First Hospital of Lanzhou University, Lanzhou 730000, China.
Xiao-Ju LiuDepartment of Grontal Respiratory Medicine, The First Hospital of Lanzhou University, Lanzhou 730000, China.
First Hospital of Lanzhou University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Some research has shown that PM2.5 causes Th1/Th2 immune imbalance and aggravates asthma. However, the exact mechanism of PM2.5 causing aggravation of asthma remains unclear. The purpose of this study was to investigate whether exposure to PM2.5 exacerbates Th1/Th2 immune imbalance through the Notch signaling pathway. Eight-week-old SPF female BALF/c mice were sensitized by ovalbumin to establish an asthma mouse model. PM2.5 exposure was carried out by aerosol inhalation of PM2.5 (510 μg/m

Indexed as

asthmaHes1immune imbalanceNotch1PM2.5signaling pathwayTh1/Th2

Identifiers

PMID37663808
PMCPMC10470343
OpenAlexW4384696966

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.