ReviewAnnals of medicine and surgery (2012)2023
Non-adherence to anti-hypertensive medications in a low-resource country Nepal: a systematic review and meta-analysis.
Review in Annals of medicine and surgery (2012), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 1 of them a synthesis that pooled it.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
12 citing papers in PubMed, 1 synthesis or guideline pooled it.
- The link between adherence to antihypertensive medications and mortality rates in patients with hypertension: a systematic review and meta-analysis of cohort studies.BMC cardiovascular disorders · 2025Pooled it
- Medication Adherence and Health-Related Quality of Life Among Hypertensive Patients in Nepal: A Cross-Sectional Study.Public health challenges · 2026Article
- Medication adherence interventions for South Asian populations with cardiovascular disease: A systematic review and narrative synthesis.PLOS global public health · 2026Article
- The prevalence and associated factors of uncontrolled blood pressure in a rural community of Nepal: A cross-sectional study.PLOS global public health · 2026Article
- Determinants of hypertension medication adherence among older adults in a resource-limited peri-urban setting, Ghana.Frontiers in public health · 2026Article
- Health-seeking challenges among older adults with hypertension in Nepal: a phenomenological study.BMC geriatrics · 2025Article
- Prevalence of Hypertension and its Associated Factors among Public Vehicle Drivers in Western Nepal: A Population-based Study.Research square · 2025Article
- Identifying Dimensions and Items for a Questionnaire to Assess Medication Adherence in Men and Women with Ischemic Heart Disease: Insights from the GENADHECAR Study.Patient preference and adherence · 2025Article
- Impact of a community health worker led intervention for improved blood pressure control in urban Nepal: an open-label cluster randomised controlled trial.The Lancet regional health. Southeast Asia · 2024Article
- Medication Adherence among Patients with Non-Communicable Diseases in a Tertiary Hospital: A Descriptive Cross-sectional Study.JNMA; journal of the Nepal Medical Association · 2024Article
- Treatment Adherence and Health-Related Quality of Life Among Patients with Hypertension at Tertiary Healthcare Facility in Lalitpur, Nepal: A Cross-Sectional Study.Patient preference and adherence · 2024Article
- Article
Corrections and comments
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Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: Nepal is a low resource country with cardiovascular diseases being the number one cause of mortality. Despite hypertension being the single most important risk factor for cardiovascular diseases, non-adherence to anti-hypertensive medications has not been assessed systematically. So, this systematic review and meta-analysis aims to analyze the prevalence of non-adherence to anti-hypertensive medications in Nepal. Methodology: This systematic review and meta-analysis was piloted in accordance with the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) statement. Electronic databases of Embase, PubMed, Scopus, Web of Science, Cochrane Library, Cinhal Plus, and Google Scholar were searched from inception till 1 February 2023. The random-effects model with 95% confidence interval (CI) was used to calculate the non-adherence rate. Results: Altogether, 14 studies with a total of 3276 hypertensive patients were included in the meta-analysis. The pooled prevalence of non-adherence to anti-hypertensive medications was 49% (95% CI: 0.37-0.62, Conclusions: This meta-analysis showed that half of the hypertensive population of Nepal are non-adherent to their anti-hypertensive medications, thereby posing a significant long-term cardiovascular consequence among Nepali population.
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Registered trials
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