Evidence map›Paper›PMID 37663720›Full record

ArticleAnnals of medicine and surgery (2012)2023

EBV-IgA antibody responses in endemic and nonendemic populations with nasopharyngeal carcinoma: tumour marker prognostication study and a cross-sectional study.

Insani Budiningsih, Sandra A W M Verkuijlen, Yoes P Dachlan, Muhammad V Arfijanto, Usman Hadi, Jaap M Middeldorp

Open access · diamondAbstract read
In one paragraph

Article in Annals of medicine and surgery (2012), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
1.2field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 5 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 2 countries.

Insani BudiningsihDoctoral Program of Medical Science, Faculty of Medicine.
Sandra A W M VerkuijlenDepartment of Pathology, Vrije Universiteit Amsterdam Amsterdam, The Netherlands.
Yoes P DachlanDepartment of Parasitology, Faculty of Medicine, Universitas Airlangga, Surabaya, Indonesia.
Muhammad V ArfijantoDepartment of Internal Medicine, Dr. Soetomo Hospital, School of Medicine.
Usman HadiDepartment of Internal Medicine, Dr. Soetomo Hospital, School of Medicine.
Jaap M MiddeldorpDepartment of Pathology, Vrije Universiteit Amsterdam Amsterdam, The Netherlands.
Vrije Universiteit Amsterdam · NLUniversitas Dr. Soetomo · IDAirlangga University · ID

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Nasopharyngeal carcinoma (NPC) is the most prevalent head and neck cancer in Indonesia, with 100% Epstein-Barr virus (EBV) infection in tumor cells. NPC is rare in the Netherlands. The involvement of EBV in NPC pathogenesis is reflected by early onset aberrant IgA antibody responses to various EBV proteins. Screening for elevated EBV-IgA levels is proposed for NPC risk assessment in endemic countries but is poorly studied in nonendemic regions. This study analyzed the overall diversity (immunoblot) as well as the prevalence and normalized levels of IgA responses to immunodominant peptide epitopes of EBV proteins VCA P18, EBNA 1, and Zebra (Zta) (N-terminus, P 125, P 130, full-length recombinant Zebra) in Indonesian (

Indexed as

EBNA 1Epstein–Barr virusIgANPCVCA P18Zebra proteins

Identifiers

PMID37663720
PMCPMC10473314
OpenAlexW4386407053

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.