ArticleTherapeutic advances in neurological disorders2023
Prevalence and risk factors of anxiety and depression in adult patients with epilepsy: a multicenter survey-based study.
Article in Therapeutic advances in neurological disorders, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.
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5 citing papers in PubMed, 11 citations in OpenAlex.
- Occurrence and clinical correlates of depressive symptoms in adults with epilepsy: A study in Georgia.Epilepsia open · 2026Article
- Clinical characteristics and factors associated with psychiatric comorbidity among people with epilepsy in Ganzi Tibetan autonomous prefecture of China: a cross-sectional study.Acta epileptologica · 2026Article
- Assessment of psychological resilience in adult patients with epilepsy: a cross-sectional study.Acta neurologica Belgica · 2025Article
- Clinical characterization and management of persons with comorbid epilepsy and depression: an expert opinion paper.Frontiers in pharmacology · 2025Review
- Using machine learning model for predicting risk of memory decline: A cross sectional study.Heliyon · 2024Article
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16 authors at 10 institutions in 1 country.
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Abstract
Background: Depression and anxiety are the most common psychiatric comorbidities in patients with epilepsy (PWE). However, they are often unrecognized and consequently untreated. Objective: The study was conducted to evaluate the prevalence and risk factors of anxiety and depression among Chinese adult PWE. Design: Cross-sectional study. Methods: Adult PWE were recruited from 13 tertiary epilepsy centers from February to September 2022. Generalized Anxiety Disorder-7 and Neurological Disorders Depression Inventory for Epilepsy were applied to evaluate anxiety and depression, respectively. Both univariate and multivariate logistic regression analyses models were performed to explore the risk factors of anxiety and depression. Results: A total of 1326 PWE were enrolled in this study. The prevalence of anxiety and depression was 31.45% and 27.30%, respectively. Being female [odds ratio (OR) = 1.467, 95% CI: 1.134-1.899; Conclusion: There were approximately 30% of PWE screened positive for anxiety or depression. Both focal and focal to bilateral TCSZ and seizure occurrence in the last 3 months were estimated as risk factors for anxiety and depression. However, the current status of treatment was not optimal.
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