Evidence map›Paper›PMID 37663243›Full record

ArticleFrontiers in pharmacology2023

Case Report: ALK rearranged locally advanced lung adenocarcinoma showing inconsistent radiographic findings and pathological responses during neoadjuvant alectinib therapy.

Peijun Cao, Qingchun Zhao, Yongwen Li, Ruifeng Shi, Guangsheng Zhu, Zihe Zhang, Hongbing Zhang, Minghui Liu, Sen Wei, Hongyu Liu and 1 more

Open access · goldAbstract readCase Reports
In one paragraph

Article in Frontiers in pharmacology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.5field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 2 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 1 institution in 1 country.

Peijun CaoDepartment of Lung Cancer Surgery, Tianjin Medical University General Hospital, Tianjin, China.
Qingchun ZhaoDepartment of Lung Cancer Surgery, Tianjin Medical University General Hospital, Tianjin, China.
Yongwen LiTianjin Lung Cancer Institute, Tianjin Key Laboratory of Lung Cancer Metastasis and Tumor Microenvironment, Tianjin Medical University General Hospital, Tianjin, China.
Ruifeng ShiDepartment of Lung Cancer Surgery, Tianjin Medical University General Hospital, Tianjin, China.
Guangsheng ZhuDepartment of Lung Cancer Surgery, Tianjin Medical University General Hospital, Tianjin, China.
Zihe ZhangDepartment of Lung Cancer Surgery, Tianjin Medical University General Hospital, Tianjin, China.
Hongbing ZhangDepartment of Lung Cancer Surgery, Tianjin Medical University General Hospital, Tianjin, China.
Minghui LiuDepartment of Lung Cancer Surgery, Tianjin Medical University General Hospital, Tianjin, China.
Sen WeiDepartment of Lung Cancer Surgery, Tianjin Medical University General Hospital, Tianjin, China.
Hongyu LiuTianjin Lung Cancer Institute, Tianjin Key Laboratory of Lung Cancer Metastasis and Tumor Microenvironment, Tianjin Medical University General Hospital, Tianjin, China.
Jun ChenDepartment of Lung Cancer Surgery, Tianjin Medical University General Hospital, Tianjin, China.
Tianjin Medical University General Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Alectinib has been approved as first-line treatment for anaplastic lymphoma kinase (ALK)-positive non-small cell lung carcinoma. Oncologists are also exploring the possibility of applying alectinib in the perioperative period. Here, we present a patient with locally advanced lung adenocarcinoma associated with

Indexed as

alectinibEML4-ALK fusion geneneoadjuvant therapypseudoresistancepulmonary adenocarcinoma

Identifiers

PMID37663243
PMCPMC10470069
OpenAlexW4385982288

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.